Literature DB >> 16360676

DNA sliding clamps: just the right twist to load onto DNA.

Daniel Barsky1, Ceslovas Venclovas.   

Abstract

Two recent papers illuminate a key step in DNA sliding clamp loading: one reveals the structure of the PCNA clamp wrapped around DNA--still open from being loaded--while the other finds that the clamp may assist this process by forming a right-handed helix upon opening.

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Year:  2005        PMID: 16360676     DOI: 10.1016/j.cub.2005.11.047

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  5 in total

1.  Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.

Authors:  Vladena Hlinkova; Guangxin Xing; Jacob Bauer; Yoon Jung Shin; Isabelle Dionne; Kanagalaghatta R Rajashankar; Stephen D Bell; Hong Ling
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2008-08-13

2.  The mechanical properties of PCNA: implications for the loading and function of a DNA sliding clamp.

Authors:  Joshua L Adelman; John D Chodera; I-Feng W Kuo; Thomas F Miller; Daniel Barsky
Journal:  Biophys J       Date:  2010-06-16       Impact factor: 4.033

3.  Recognition of the ring-opened state of proliferating cell nuclear antigen by replication factor C promotes eukaryotic clamp-loading.

Authors:  John A Tainer; J Andrew McCammon; Ivaylo Ivanov
Journal:  J Am Chem Soc       Date:  2010-06-02       Impact factor: 15.419

4.  Expression of a novel peptide derived from PCNA damages DNA and reverses cisplatin resistance.

Authors:  Robert G Lingeman; Robert J Hickey; Linda H Malkas
Journal:  Cancer Chemother Pharmacol       Date:  2014-09-05       Impact factor: 3.333

5.  Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways.

Authors:  Youngjo Kim; Edward T Kipreos
Journal:  Cell Div       Date:  2007-06-12       Impact factor: 5.130

  5 in total

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