Literature DB >> 16359615

Serendipity strikes twice: the discovery and rediscovery of defective ribosomal products (DRiPS).

J W Yewdell1.   

Abstract

Here I recount how the remarkably large fraction of rapidly degraded nascent proteins was discovered through serendipity not once, but twice. This story is used as a canvas for discussing how the imperfections in human nature retard scientific progress.

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Year:  2005        PMID: 16359615

Source DB:  PubMed          Journal:  Cell Mol Biol (Noisy-le-grand)        ISSN: 0145-5680            Impact factor:   1.770


  11 in total

1.  A unified mechanism for protein folding: predetermined pathways with optional errors.

Authors:  Mallela M G Krishna; S Walter Englander
Journal:  Protein Sci       Date:  2007-03       Impact factor: 6.725

2.  Branching in the sequential folding pathway of cytochrome c.

Authors:  Mallela M G Krishna; Haripada Maity; Jon N Rumbley; S Walter Englander
Journal:  Protein Sci       Date:  2007-07-27       Impact factor: 6.725

Review 3.  Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection.

Authors:  Natalia B Nedelsky; Peter K Todd; J Paul Taylor
Journal:  Biochim Biophys Acta       Date:  2008-10-10

Review 4.  Protein folding and misfolding: mechanism and principles.

Authors:  S Walter Englander; Leland Mayne; Mallela M G Krishna
Journal:  Q Rev Biophys       Date:  2008-04-14       Impact factor: 5.318

5.  Selective vulnerability of neurons to acute toxicity after proteasome inhibitor treatment: implications for oxidative stress and insolubility of newly synthesized proteins.

Authors:  Kalavathi Dasuri; Philip J Ebenezer; Le Zhang; Sun Ok Fernandez-Kim; Romina M Uranga; Elena Gavilán; Alessia Di Blasio; Jeffrey N Keller
Journal:  Free Radic Biol Med       Date:  2010-08-01       Impact factor: 7.376

Review 6.  Modulation of the Translational Landscape During Herpesvirus Infection.

Authors:  Britt A Glaunsinger
Journal:  Annu Rev Virol       Date:  2015-07-02       Impact factor: 10.431

7.  How is the balance between protein synthesis and degradation achieved?

Authors:  Stephen Rothman
Journal:  Theor Biol Med Model       Date:  2010-06-23       Impact factor: 2.432

Review 8.  Ubiquitin-independent proteasomal degradation.

Authors:  Jenny Erales; Philip Coffino
Journal:  Biochim Biophys Acta       Date:  2013-05-14

9.  Influence of translation efficiency of homologous viral proteins on the endogenous presentation of CD8+ T cell epitopes.

Authors:  Judy Tellam; Mark H Fogg; Michael Rist; Geoff Connolly; David Tscharke; Natasha Webb; Lea Heslop; Fred Wang; Rajiv Khanna
Journal:  J Exp Med       Date:  2007-02-20       Impact factor: 14.307

10.  mRNA Structural constraints on EBNA1 synthesis impact on in vivo antigen presentation and early priming of CD8+ T cells.

Authors:  Judy T Tellam; Jie Zhong; Lea Lekieffre; Purnima Bhat; Michelle Martinez; Nathan P Croft; Warren Kaplan; Ross L Tellam; Rajiv Khanna
Journal:  PLoS Pathog       Date:  2014-10-09       Impact factor: 6.823

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