OBJECTIVE: Efficacy of salvage surgery after radiotherapy failure in patients with laryngeal cancer. MATERIAL AND METHODS: Retrospective analysis of 121 patients treated in our clinic between 1980 and 2003 (supraglottis--86 patients, glottis--35). In 70% of patients T-stage was T3 and T4 and regional metastases were present in 56% of cases. We performed statistical analysis of recurrence rates and 5-years survival according to Kaplan-Meier method. RESULTS: Glottic localization (p = 0.02) and extracapsular spread (p = 0.03) were significant factors of final outcome. Local and regional stage was not significant factor of recurrence. Disease free 5-year survival was 53%. CONCLUSION: Salvage surgery is a reasonable method that could save about 50% of patients after radiotherapy failure.
OBJECTIVE: Efficacy of salvage surgery after radiotherapy failure in patients with laryngeal cancer. MATERIAL AND METHODS: Retrospective analysis of 121 patients treated in our clinic between 1980 and 2003 (supraglottis--86 patients, glottis--35). In 70% of patients T-stage was T3 and T4 and regional metastases were present in 56% of cases. We performed statistical analysis of recurrence rates and 5-years survival according to Kaplan-Meier method. RESULTS: Glottic localization (p = 0.02) and extracapsular spread (p = 0.03) were significant factors of final outcome. Local and regional stage was not significant factor of recurrence. Disease free 5-year survival was 53%. CONCLUSION: Salvage surgery is a reasonable method that could save about 50% of patients after radiotherapy failure.