Literature DB >> 16354424

A window of opportunity: declining rates of hepatitis B virus infection among injection drug users in Rio de Janeiro, and prospects for targeted hepatitis B vaccination.

Sabrina A N Oliveira1, Mariana A Hacker, M Lourdes A Oliveira, Clara F T Yoshida, Paulo R Telles, Francisco I Bastos.   

Abstract

OBJECTIVES: To measure hepatitis B virus (HBV) infection rates among injection drug users in Rio de Janeiro, Brazil, and to report their knowledge of and attitudes toward hepatitis and HBV vaccination.
METHODS: 609 injection drug users recruited in Rio de Janeiro between 1999 and 2001 answered a questionnaire and were tested for hepatitis B and other blood-borne infections. Questions covered sociodemographic information, alcohol and illicit drug consumption, drug injection and sexual practices, medical history, and knowledge about HIV, AIDS and viral hepatitis.
RESULTS: The prevalence of HBV infection was 27.1%, with 3.4% of the sample positive for HbsAg (active infection) and 0.8% positive for anti-HBs (indicating previous HBV vaccination). Most interviewees (81.3%) were aware of at least one form of viral hepatitis and received information from many different sources. In agreement with laboratory findings, 96.7% of the interviewees stated they had never been vaccinated against hepatitis B, but almost all unvaccinated interviewees (97.8%) said they would volunteer to be vaccinated if HBV vaccination were available.
CONCLUSIONS: Few of the injection drug users surveyed had ever been vaccinated against HBV. Although most were aware of the risks posed by viral hepatitis, this awareness seldom translated into consistent behavioral change. The participants' willingness to be vaccinated against HBV suggests that the implementation of vaccination for this population may help decrease rates of hepatitis B infection.

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Year:  2005        PMID: 16354424     DOI: 10.1590/s1020-49892005000900007

Source DB:  PubMed          Journal:  Rev Panam Salud Publica        ISSN: 1020-4989


  2 in total

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Authors:  Samuel R Friedman; Pedro Mateu-Gelabert; Milagros Sandoval; Holly Hagan; Don C Des Jarlais
Journal:  BMC Public Health       Date:  2008-03-20       Impact factor: 3.295

2.  Seroprevalence of Bartonella spp., Coxiella burnetii, and Hantavirus among people who inject drugs in Rio de Janeiro, Brazil: a retrospective assessment of a biobank.

Authors:  Tatiana Rozental; Anamaria Szrajbman Vaz da Silva; Renata Carvalho de Oliveira; Alexsandra Rodrigues de Mendonça Favacho; Maria de Lourdes Aguiar Oliveira; Francisco Inácio Bastos; Elba Regina Sampaio de Lemos
Journal:  Rev Inst Med Trop Sao Paulo       Date:  2018-07-19       Impact factor: 1.846

  2 in total

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