| Literature DB >> 16354331 |
Steven D Mawhorter1, Anne Sierk, Susan M Staugaitis, Robin K Avery, Ronald Sobecks, Richard A Prayson, Gary W Procop, Belinda Yen-Lieberman.
Abstract
West Nile virus (WNV) infections are potentially life threatening in immunocompromised hosts. Currently, the best diagnostic test is serology. Reverse-transcriptase polymerase chain reaction (RT-PCR) testing has a role, but, because WNV is a cell-associated neurotropic virus, RT-PCR results are frequently negative even in cases of active infection. We present a case in which serology results were persistently negative because the patient was immunocompromised following lymphoma treatment. The role of humoral immunity in resolution of WNV is also discussed.Entities:
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Year: 2005 PMID: 16354331 DOI: 10.3816/CLM.2005.n.053
Source DB: PubMed Journal: Clin Lymphoma Myeloma ISSN: 1557-9190