| Literature DB >> 16354077 |
Takumi Kimura1, Kiyohiko Kawai, Tetsuro Majima.
Abstract
[graph: see text] We describe the synthesis of new environmentally sensitive fluorescence probes to elucidate DNA structures. DNA oligonucleotides containing fluorophore dan (6-(dimethylamino)-2-acylnaphthalene)-modified dC or dG were able to monitor the microenvironmental changes in both the major and minor grooves of DNA with a B- to A-DNA conformational transition and RNA hybridization.Entities:
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Year: 2005 PMID： 16354077 DOI： 10.1021/ol052473m
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005