Literature DB >> 16351353

No, it is not possible to be schizophrenic yet neuropsychologically normal.

Christopher M Wilk1, James M Gold, Robert P McMahon, Katherine Humber, Virginia N Iannone, Robert W Buchanan.   

Abstract

Cognitive impairment is well documented in schizophrenia, though some reports have been interpreted to suggest that it is possible to have schizophrenia without neuropsychological impairment. The authors tested this by comparing the neuropsychological profiles of closely matched patients with schizophrenia and healthy comparison participants. Sixty-four patients with schizophrenia and 64 healthy comparison cases, matched to within 3 Full-Scale IQ points, were tested using the Wechsler Adult Intelligence Scale (3rd ed.; D. Wechsler, 1997b) and the Wechsler Memory Scale (3rd ed.; D. Wechsler, 1997c). Neuropsychological profiles for these groups were markedly different, with the group of patients with schizophrenia exhibiting performance deficits in memory and speeded visual processing but superior verbal comprehension and perceptual organization relative to the group of healthy comparison participants matched on Full-Scale IQ. Thus, scoring in the normal range does not preclude neuropsychological abnormality in schizophrenia, confirming that neuropsychological impairment is a core feature of the illness. Copyright (c) 2005 APA, all rights reserved.

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Year:  2005        PMID: 16351353     DOI: 10.1037/0894-4105.19.6.778

Source DB:  PubMed          Journal:  Neuropsychology        ISSN: 0894-4105            Impact factor:   3.295


  37 in total

Review 1.  Functional impairment in people with schizophrenia: focus on employability and eligibility for disability compensation.

Authors:  Philip D Harvey; Robert K Heaton; William T Carpenter; Michael F Green; James M Gold; Michael Schoenbaum
Journal:  Schizophr Res       Date:  2012-04-13       Impact factor: 4.939

2.  Abnormal responses to monetary outcomes in cortex, but not in the basal ganglia, in schizophrenia.

Authors:  James A Waltz; Julie B Schweitzer; Thomas J Ross; Pradeep K Kurup; Betty J Salmeron; Emma J Rose; James M Gold; Elliot A Stein
Journal:  Neuropsychopharmacology       Date:  2010-08-18       Impact factor: 7.853

3.  Toward a terminology for functional recovery in schizophrenia: is functional remission a viable concept?

Authors:  Philip D Harvey; Alan S Bellack
Journal:  Schizophr Bull       Date:  2009-01-06       Impact factor: 9.306

4.  Brain Structure in Neuropsychologically Defined Subgroups of Schizophrenia and Psychotic Bipolar Disorder.

Authors:  Neil D Woodward; Stephan Heckers
Journal:  Schizophr Bull       Date:  2015-04-22       Impact factor: 9.306

5.  Social cognitive training for schizophrenia: a meta-analytic investigation of controlled research.

Authors:  Matthew M Kurtz; Christi L Richardson
Journal:  Schizophr Bull       Date:  2011-04-27       Impact factor: 9.306

6.  Impaired visual object processing across an occipital-frontal-hippocampal brain network in schizophrenia: an integrated neuroimaging study.

Authors:  Pejman Sehatpour; Elisa C Dias; Pamela D Butler; Nadine Revheim; David N Guilfoyle; John J Foxe; Daniel C Javitt
Journal:  Arch Gen Psychiatry       Date:  2010-08

7.  Memory profiles in schizophrenia: categorization validity and stability.

Authors:  Morris D Bell; Jason K Johannesen; Tamasine C Greig; Bruce E Wexler
Journal:  Schizophr Res       Date:  2010-01-20       Impact factor: 4.939

Review 8.  What do we know about neuropsychological aspects of schizophrenia?

Authors:  Barton W Palmer; Sharron E Dawes; Robert K Heaton
Journal:  Neuropsychol Rev       Date:  2009-07-30       Impact factor: 7.444

9.  Prefrontal-Thalamic Anatomical Connectivity and Executive Cognitive Function in Schizophrenia.

Authors:  Monica Giraldo-Chica; Baxter P Rogers; Stephen M Damon; Bennett A Landman; Neil D Woodward
Journal:  Biol Psychiatry       Date:  2017-09-28       Impact factor: 13.382

10.  The relationship between IQ, memory, executive function, and processing speed in recent-onset psychosis: 1-year stability and clinical outcome.

Authors:  Verity C Leeson; Thomas R E Barnes; Masuma Harrison; Elizabeth Matheson; Isobel Harrison; Stanley H Mutsatsa; Maria A Ron; Eileen M Joyce
Journal:  Schizophr Bull       Date:  2008-08-04       Impact factor: 9.306

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