Literature DB >> 16349765

Inactivation of Venezuelan Equine Encephalomyelitis Virus by gamma-Radiation.

M Reitman1, H R Tribble.   

Abstract

Exposure of Venezuelan equine encephalomyelitis (VEE) virus (at -70 C) to 6 x 10 r gamma-radiation (Co) resulted in loss of lethality for young adult mice and guinea pigs, and loss of capacity to produce plaques or cytopathic effects in tissue culture. The suckling mouse was more sensitive for detecting live virus in radiated suspensions than was the adult mouse or guinea pig. Live virus was demonstrable in preparations exposed to 6 x 10 r but not in suspensions exposed to 8 x 10 r and more. The rate of inactivation of VEE virus by gamma-radiation was an exponential function of the dosage.

Entities:  

Year:  1967        PMID： 16349765      PMCID： PMC547232          DOI： 10.1128/am.15.6.1456-1459.1967

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN： 0003-6919


  6 in total

1.  A chemically defined medium for growth of animal cells in suspension.

Authors:  S C NAGLE; H R TRIBBLE; R E ANDERSON; N D GARY
Journal:  Proc Soc Exp Biol Med       Date:  1963-02

2.  Factors influencing inactivation of infectivity and hemagglutinin of influenza virus by gamma radiation.

Authors:  J R POLLEY
Journal:  Can J Microbiol       Date:  1961-08       Impact factor: 2.419

3.  The antigenicity of gamma-irradiated vaccinia virus.

Authors:  C KAPLAN
Journal:  J Hyg (Lond)       Date:  1960-12

4.  Venezulean equine encephalomyelitis; laboratory aspects of fourteen human cases following vaccination and attempts to isolate the virus from the vaccine.

Authors:  D G SMITH; H K MAMAY; R G MARSHALL; J C WAGNER
Journal:  Am J Hyg       Date:  1956-03

5.  Inactivation of some animal viruses with gamma radiation from cobalt-60.

Authors:  R T JORDAN; L L KEMPE
Journal:  Proc Soc Exp Biol Med       Date:  1956-02

6.  Pathogenesis of Venezuelan equine encephalomyelitis virus. I. Infection in suckling mice.

Authors:  W D Kundin; C Liu; P Rodina
Journal:  J Immunol       Date:  1966-01       Impact factor: 5.422
  6 in total
  9 in total

1.  Inactivation of rubella virus by gamma radiation.

Authors:  M T Kenny; K L Albright; J B Emery; J L Bittle
Journal:  J Virol       Date:  1969-12       Impact factor: 5.103

2.  Gamma radiation inactivation of coxsackievirus B-2.

Authors:  R Sullivan; P V Scarpino; A C Fassolitis; E P Larkin; J T Peeler
Journal:  Appl Microbiol       Date:  1973-07

3.  Nonviable Venezuelan equine encephalomyelitis hemagglutinin prepared from tissue cultures by gamma radiation.

Authors:  M Reitman
Journal:  Appl Microbiol       Date:  1969-08

4.  Inactivation of rabies diagnostic reagents by gamma radiation.

Authors:  W C Gamble; W A Chappell; E H George
Journal:  J Clin Microbiol       Date:  1980-11       Impact factor: 5.948

5.  Inactivation of thirty viruses by gamma radiation.

Authors:  R Sullivan; A C Fassolitis; E P Larkin; R B Read; J T Peeler
Journal:  Appl Microbiol       Date:  1971-07

6.  Gamma-irradiated Venezuelan equine encephalitis vaccines.

Authors:  M Reitman; H R Tribble; L Green
Journal:  Appl Microbiol       Date:  1970-05

7.  Immunogenicity of purified venezuelan equine encephalitis virus inactivated by ionizing radiation.

Authors:  J Gruber
Journal:  Infect Immun       Date:  1971-04       Impact factor: 3.441

8.  Immunogenicity of rabies virus inactivated by -propiolactone, acetylethyleneimine, and ionizing irradiation.

Authors:  T J Wiktor; H G Aaslestad; M M Kaplan
Journal:  Appl Microbiol       Date:  1972-05

9.  Purification, concentration, and inactivation of Venezuelan equine encephalitis virus.

Authors:  J Gruber
Journal:  Appl Microbiol       Date:  1970-09
  9 in total

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