| Literature DB >> 163492 |
T B Strom, R A Bear, C B Carpenter.
Abstract
Physiologic concentrations of insulin enhance the ability of cytotoxic lymphocytes to injure target cells. The effect of insulin closely resembles the action of cholinomimetics and guanosine 3',5'-monophosphate upon this system. Since both insulin and cholinomimetics elevate intracellular concentrations of guanosine 3',5'-monophosphate, a common mode of action is suggested.Entities:
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Year: 1975 PMID: 163492 DOI: 10.1126/science.163492
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728