Literature DB >> 163491

Phosphorylation of lymphocyte nuclear acidic proteins: regulation by cyclic nucleotides.

E M Johnson, J W Hadden.   

Abstract

Guanosine 3',5'-monophosphate (cyclic GMP) and cholinergic agents stimulate incorporation of phosphate into specific nuclear acidic proteins of horse peripheral blood lymphocytes. Agents that raise intracellular adenosine 3',5'-monophosphate (cyclic AMP) inhibit nuclear acidic protein phosphorylation. The opposing effects of cyclic GMP and cyclic AMP upon nuclear protein phosphorylation parallel the effects of the cyclic nucleotides upon induction of lymphocyte proliferation.

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Year:  1975        PMID: 163491     DOI: 10.1126/science.163491

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  8 in total

1.  Association of cyclic GMP with gene expression of polytene chromosomes of Drosophila melanogaster.

Authors:  W A Spruill; D R Hurwitz; J C Lucchesi; A L Steiner
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

2.  Induction of DNA synthesis in isolated nuclei by cytoplasmic factors: inhibition by protease inhibitors.

Authors:  R L Wong; J K Gutowski; M Katz; R H Goldfarb; S Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

3.  Complex of DNA with chromatin proteins investigated by isopycnic centrifugation in metrizamide.

Authors:  J Rzeszowska-Wolny; J Filipski; S Gröbner; M Chorazy
Journal:  Nucleic Acids Res       Date:  1978-12       Impact factor: 16.971

4.  Effects of concanavalin A and a succinylated derivative on lymphocyte proliferation and cyclic nucleotide levels.

Authors:  J W Hadden; E M Hadden; J R Sadlik; R G Coffey
Journal:  Proc Natl Acad Sci U S A       Date:  1976-05       Impact factor: 11.205

5.  Regulation of hepatic nuclear guanylate cyclase.

Authors:  H S Earp; P Smith; S H Huang Ong; A L Steiner
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

6.  Immunohistochemical studies of cyclic guanosine monophosphate and nuclear function.

Authors:  E M Rosenberg; J G Conway; S M Tucci; E W Doucet
Journal:  J Clin Invest       Date:  1980-10       Impact factor: 14.808

7.  Activation of lymphocytes by brominated nucleoside and cyclic nucleotide analogues: implications for the "second messenger" function of cyclic GMP.

Authors:  M G Goodman; W O Weigle
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

8.  Induction and properties of cytoplasmic factor(s) which enhance nuclear nonhistone protein phosphorylation in lymphocytes stimulated by anti-Ig.

Authors:  Y Nishizawa; T Kishimoto; H Kikutani; Y Yamamura
Journal:  J Exp Med       Date:  1977-09-01       Impact factor: 14.307

  8 in total

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