Literature DB >> 16346627

Bioconversion of Lithocholic Acid Under Anaerobic Conditions by Pseudomonas sp. Strain NCIB 10590.

R W Owen1, R F Bilton.   

Abstract

The biotransformation of lithocholic acid by Pseudomonas sp. strain NCIB 10590 under anaerobic conditions was studied. The major products were identified as androsta-1,4-diene-3,17-dione and 3-oxochol-4-ene-24-oic acid. The minor products included 17beta-hydroxyandrost-4-ene-3-one, 17beta-hydroxyandrosta-1,4-diene-3-one, 3-oxo-5beta-cholan-24-oic acid, 3-oxochola-1,4-diene-24-oic acid, 3-oxopregn-4-ene-20-carboxylic acid, and 3-oxopregna-1,4-diene-20-carboxylic acid. Anaerobiosis increases the number of metabolites produced by Pseudomonas sp. NCIB 10590 from lithocholic acid.

Entities:  

Year:  1984        PMID: 16346627      PMCID: PMC241574          DOI: 10.1128/aem.48.3.606-609.1984

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN: 0099-2240            Impact factor:   4.792


  16 in total

1.  Investigation of the gastrointestinal bacterial flora.

Authors:  P Borriello; M Hudson; M Hill
Journal:  Clin Gastroenterol       Date:  1978-05

2.  The degradation of cholesterol by Escherichia coli isolated from human faeces [proceedings].

Authors:  R W Owen; M E Tenneson; R F Bilton; A N Mason
Journal:  Biochem Soc Trans       Date:  1978       Impact factor: 5.407

3.  The degradation of hyodeoxycholic acid by Pseudomon as spp. N.C.I.B. 10590.

Authors:  M E Tenneson; J D Baty; R F Bilton; A N Mason
Journal:  J Steroid Biochem       Date:  1979-09       Impact factor: 4.292

4.  The degradation of cholesterol by Pseudomonas sp. NCIB 10590 under aerobic conditions.

Authors:  R W Owen; A N Mason; R F Bilton
Journal:  J Lipid Res       Date:  1983-11       Impact factor: 5.922

5.  The metabolism of lithocholic acid and lithocholic acid-3-alpha-sulfate by human fecal bacteria.

Authors:  S P Borriello; R W Owen
Journal:  Lipids       Date:  1982-07       Impact factor: 1.880

6.  The degradation of lithocholic acid by Pseudomonas Spp NCIB 10590.

Authors:  M E Tenneson; R F Bilton; A N Mason
Journal:  FEBS Lett       Date:  1978-07-01       Impact factor: 4.124

7.  The degradation of cholic acid by Pseudomonas sp. N.C.I.B. 10590.

Authors:  M E Tenneson; J D Baty; R F Bilton; A N Mason
Journal:  Biochem J       Date:  1979-12-15       Impact factor: 3.857

8.  The biotransformation of hyodeoxycholic acid by Pseudomonas sp. NCIB 10590 under anaerobic conditions.

Authors:  R W Owen; R F Bilton
Journal:  J Steroid Biochem       Date:  1983-09       Impact factor: 4.292

9.  Microbiological degradation of bile acids. Ring A cleavage and 7alpha, 12alpha-dehydroxylation of cholic acid by Arthrobacter simplex.

Authors:  S Hayakawa; Y Kanematsu; T Fujiwara
Journal:  Biochem J       Date:  1969-11       Impact factor: 3.857

10.  Identification of mono- and dihydroxy bile acids in human feces by gas-liquid chromatography and mass spectrometry.

Authors:  P Eneroth; B Gordon; R Ryhage; J Sjövall
Journal:  J Lipid Res       Date:  1966-07       Impact factor: 5.922

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  1 in total

1.  Oxidative Stress-Mediated Brain Dehydroepiandrosterone (DHEA) Formation in Alzheimer's Disease Diagnosis.

Authors:  Georges Rammouz; Laurent Lecanu; Vassilios Papadopoulos
Journal:  Front Endocrinol (Lausanne)       Date:  2011-11-08       Impact factor: 5.555

  1 in total

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