| Literature DB >> 16346627 |
Abstract
The biotransformation of lithocholic acid by Pseudomonas sp. strain NCIB 10590 under anaerobic conditions was studied. The major products were identified as androsta-1,4-diene-3,17-dione and 3-oxochol-4-ene-24-oic acid. The minor products included 17beta-hydroxyandrost-4-ene-3-one, 17beta-hydroxyandrosta-1,4-diene-3-one, 3-oxo-5beta-cholan-24-oic acid, 3-oxochola-1,4-diene-24-oic acid, 3-oxopregn-4-ene-20-carboxylic acid, and 3-oxopregna-1,4-diene-20-carboxylic acid. Anaerobiosis increases the number of metabolites produced by Pseudomonas sp. NCIB 10590 from lithocholic acid.Entities:
Year: 1984 PMID: 16346627 PMCID: PMC241574 DOI: 10.1128/aem.48.3.606-609.1984
Source DB: PubMed Journal: Appl Environ Microbiol ISSN: 0099-2240 Impact factor: 4.792