Literature DB >> 16344528

Leptin, ghrelin, and adiponectin in epileptic patients treated with valproic acid.

R Greco1, G Latini, F Chiarelli, P Iannetti, A Verrotti.   

Abstract

The authors studied 40 epileptic patients treated with valproate and 40 healthy controls for at least 2 years. At the end of follow-up, 15 epileptic patients (37.5%) had development of obesity. They showed circulating leptin and insulin levels significantly higher and ghrelin and adiponectin levels significantly lower than those of patients who did not gain weight.

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Year:  2005        PMID： 16344528     DOI： 10.1212/01.wnl.0000187074.27586.d1

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  20 in total

1.  Plasma leptin, neuropeptide Y, ghrelin, and adiponectin levels and carotid artery intima media thickness in epileptic children treated with valproate.

Authors:  Huseyin Tokgoz; Kursad Aydin; Bulent Oran; Aysel Kiyici
Journal:  Childs Nerv Syst       Date:  2012-05-30       Impact factor: 1.475

Review 2.  The impact of leptin on perinatal development and psychopathology.

Authors:  Jeanette C Valleau; Elinor L Sullivan
Journal:  J Chem Neuroanat       Date:  2014-05-23       Impact factor: 3.052

3.  HDAC5-mTORC1 Interaction in Differential Regulation of Ghrelin and Nucleobindin 2 (NUCB2)/Nesfatin-1.

Authors:  Liangxiao Ma; Hong Tang; Yue Yin; Ruili Yu; Jing Zhao; Yin Li; Michael W Mulholland; Weizhen Zhang
Journal:  Mol Endocrinol       Date:  2015-09-10

Review 4.  Valproic acid and nonalcoholic fatty liver disease: A possible association?

Authors:  Edoardo Farinelli; David Giampaoli; Anja Cenciarini; Ephraim Cercado; Alberto Verrotti
Journal:  World J Hepatol       Date:  2015-05-28

Review 5.  Impact of Antiseizure Medications on Appetite and Weight in Children.

Authors:  Ersida Buraniqi; Hicham Dabaja; Elaine C Wirrell
Journal:  Paediatr Drugs       Date:  2022-05-21       Impact factor: 3.022

6.  Effect of valproic acid on body weight, food intake, physical activity and hormones: results of a randomized controlled trial.

Authors:  C K Martin; H Han; S D Anton; F L Greenway; S R Smith
Journal:  J Psychopharmacol       Date:  2008-06-26       Impact factor: 4.153

7.  Nesfatin-1 and ghrelin levels in serum and saliva of epileptic patients: hormonal changes can have a major effect on seizure disorders.

Authors:  Suleyman Aydin; Ersel Dag; Yusuf Ozkan; Fazilet Erman; Adile Ferda Dagli; Nermin Kilic; Ibrahim Sahin; Fikret Karatas; Tahir Yoldas; Abdullah Onder Barim; Yalcin Kendir
Journal:  Mol Cell Biochem       Date:  2009-03-05       Impact factor: 3.396

Review 8.  Ghrelin and Neurodegenerative Disorders-a Review.

Authors:  Limin Shi; Xixun Du; Hong Jiang; Junxia Xie
Journal:  Mol Neurobiol       Date:  2016-01-26       Impact factor: 5.590

9.  Inactivation of the constitutively active ghrelin receptor attenuates limbic seizure activity in rodents.

Authors:  Jeanelle Portelli; Leen Thielemans; Luc Ver Donck; Ellen Loyens; Jessica Coppens; Najat Aourz; Jeroen Aerssens; Katia Vermoesen; Ralph Clinckers; Anneleen Schallier; Yvette Michotte; Dieder Moechars; Graham L Collingridge; Zuner A Bortolotto; Ilse Smolders
Journal:  Neurotherapeutics       Date:  2012-07       Impact factor: 7.620

Review 10.  Targeting histone deacetylases for the treatment of disease.

Authors:  M W Lawless; S Norris; K J O'Byrne; S G Gray
Journal:  J Cell Mol Med       Date:  2008-11-03       Impact factor: 5.310
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