Literature DB >> 16344329

Expression of tandem P domain K+ channel, TREK-1, in the rat carotid body.

Y Yamamoto1, K Taniguchi.   

Abstract

TREK-1 is one of the important potassium channels for regulating membrane excitability. To examine the distribution of TREK-1 in the rat carotid body, we performed RT-PCR for mRNA expression and in situ hybridization and immunohistochemistry for tissue distribution of TREK-1. RT-PCR detected mRNA expression of TREK-1 in the carotid body. Furthermore, in situ hybridization revealed the localization of TREK-1 mRNA in the glomus cells. TREK-1 immunoreactivity was mainly distributed in the glomus cells and nerve fibers in the carotid body. TREK-1 may modulate potassium current of glomus cells and/or afferent nerve endings in the rat carotid body.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 16344329     DOI： 10.1369/jhc.5A6755.2005

Source DB:  PubMed          Journal:  J Histochem Cytochem        ISSN： 0022-1554            Impact factor:   2.479


  12 in total

Review 1.  Peripheral chemoreceptors: function and plasticity of the carotid body.

Authors:  Prem Kumar; Nanduri R Prabhakar
Journal:  Compr Physiol       Date:  2012-01       Impact factor: 9.090

2.  Single cell transcriptome analysis of mouse carotid body glomus cells.

Authors:  Ting Zhou; Ming-Shan Chien; Safa Kaleem; Hiroaki Matsunami
Journal:  J Physiol       Date:  2016-04-13       Impact factor: 5.182

3.  The human carotid body transcriptome with focus on oxygen sensing and inflammation--a comparative analysis.

Authors:  Souren Mkrtchian; Jessica Kåhlin; Anette Ebberyd; Constancio Gonzalez; Diego Sanchez; Alexander Balbir; Eric W Kostuk; Machiko Shirahata; Malin Jonsson Fagerlund; Lars I Eriksson
Journal:  J Physiol       Date:  2012-05-21       Impact factor: 5.182

Review 4.  Are Multiple Mitochondrial Related Signalling Pathways Involved in Carotid Body Oxygen Sensing?

Authors:  Andrew P Holmes; Agnieszka Swiderska; Demitris Nathanael; Hayyaf S Aldossary; Clare J Ray; Andrew M Coney; Prem Kumar
Journal:  Front Physiol       Date:  2022-05-31       Impact factor: 4.755

5.  Distribution of voltage-gated potassium and hyperpolarization-activated channels in sensory afferent fibers in the rat carotid body.

Authors:  Maria Buniel; Patricia A Glazebrook; Angelina Ramirez-Navarro; Diana L Kunze
Journal:  J Comp Neurol       Date:  2008-10-01       Impact factor: 3.215

6.  Fluoresceinated peanut agglutinin (PNA) is a marker for live O(2) sensing glomus cells in rat carotid body.

Authors:  I Kim; D J Yang; D F Donnelly; J L Carroll
Journal:  Adv Exp Med Biol       Date:  2009       Impact factor: 2.622

7.  Heteromeric TASK-1/TASK-3 is the major oxygen-sensitive background K+ channel in rat carotid body glomus cells.

Authors:  Donghee Kim; Eric J Cavanaugh; Insook Kim; John L Carroll
Journal:  J Physiol       Date:  2009-04-29       Impact factor: 5.182

8.  AMP-activated protein kinase inhibits TREK channels.

Authors:  Orsolya Kréneisz; Justin P Benoit; Douglas A Bayliss; Daniel K Mulkey
Journal:  J Physiol       Date:  2009-12-15       Impact factor: 5.182

9.  Modulation of TASK-like background potassium channels in rat arterial chemoreceptor cells by intracellular ATP and other nucleotides.

Authors:  Rodrigo Varas; Christopher N Wyatt; Keith J Buckler
Journal:  J Physiol       Date:  2007-07-05       Impact factor: 5.182

10.  Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 and TASK-3 channels in mouse carotid body type-1 cells.

Authors:  Philip J Turner; Keith J Buckler
Journal:  J Physiol       Date:  2013-09-16       Impact factor: 5.182
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.