Literature DB >> 16343678

Iontophoresis: a non-invasive ocular drug delivery.

Esther Eljarrat-Binstock1, Abraham J Domb.   

Abstract

Iontophoresis as a non-invasive technique for ocular drug delivery has been investigated for many years. This paper provides an overview of the approaches currently used in the development of the ocular iontophoretic device, the essential features of this procedure and the reported toxicity. This review focuses on the experimental results after transcorneal and transscleral iontophoresis of different drugs, emphasizing the current density applied and the treatment duration used by the investigators.

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Mesh：

Year:  2005        PMID： 16343678     DOI： 10.1016/j.jconrel.2005.09.049

Source DB:  PubMed          Journal:  J Control Release        ISSN： 0168-3659            Impact factor:   9.776


  41 in total

1.  Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications.

Authors:  Henry F Edelhauser; Cheryl L Rowe-Rendleman; Michael R Robinson; Daniel G Dawson; Gerald J Chader; Hans E Grossniklaus; Kay D Rittenhouse; Clive G Wilson; David A Weber; Baruch D Kuppermann; Karl G Csaky; Timothy W Olsen; Uday B Kompella; V Michael Holers; Gregory S Hageman; Brian C Gilger; Peter A Campochiaro; Scott M Whitcup; Wai T Wong
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-11       Impact factor: 4.799

2.  Sustained release micellar carrier systems for iontophoretic transport of dexamethasone across human sclera.

Authors:  Poonam Chopra; Jinsong Hao; S Kevin Li
Journal:  J Control Release       Date:  2012-01-27       Impact factor: 9.776

Review 3.  New techniques for drug delivery to the posterior eye segment.

Authors:  Esther Eljarrat-Binstock; Jacob Pe'er; Abraham J Domb
Journal:  Pharm Res       Date:  2010-02-13       Impact factor: 4.200

4.  Early effects of corneal collagen cross-linking by iontophoresis in ex vivo human corneas.

Authors:  Rita Mencucci; Stefano Ambrosini; Iacopo Paladini; Eleonora Favuzza; Carlotta Boccalini; Giulia Raugei; Gabriella Barbara Vannelli; Mirca Marini
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-11-04       Impact factor: 3.117

5.  ISOPT Clinical Hot Topic Panel Discussion on Ocular Drug Delivery.

Authors:  Uday B Kompella; Abraham Domb; Arto Urtti; Ashwath Jayagopal; Clive G Wilson; Diane Tang-Liu
Journal:  J Ocul Pharmacol Ther       Date:  2019-06-28       Impact factor: 2.671

6.  A flexible device for ocular iontophoretic drug delivery.

Authors:  Yushi Zhang; Yao Chen; Xiaoxue Yu; Yangjia Qi; Yufeng Chen; Yuxi Liu; Yuntao Hu; Zhihong Li
Journal:  Biomicrofluidics       Date:  2016-02-24       Impact factor: 2.800

7.  Transscleral Iontophoresis for Noninvasive Ocular Drug Delivery of Macromolecules.

Authors:  Sarah Molokhia; Kongnara Papangkorn; Charlotte Butler; John W Higuchi; Balbir Brar; Balamurali Ambati; S Kevin Li; William I Higuchi
Journal:  J Ocul Pharmacol Ther       Date:  2020-03-05       Impact factor: 2.671

8.  Examination of barriers and barrier alteration in transscleral iontophoresis.

Authors:  Sarah A Molokhia; Eun-Kee Jeong; William I Higuchi; S Kevin Li
Journal:  J Pharm Sci       Date:  2008-02       Impact factor: 3.534

9.  Modeling iontophoretic drug delivery in a microfluidic device.

Authors:  Maryam Moarefian; Rafael V Davalos; Danesh K Tafti; Luke E Achenie; Caroline N Jones
Journal:  Lab Chip       Date:  2020-09-01       Impact factor: 6.799

10.  Influence of drug lipophilicity on drug release from sclera after iontophoretic delivery of mixed micellar carrier system to human sclera.

Authors:  Poonam Chopra; Jinsong Hao; S Kevin Li
Journal:  J Pharm Sci       Date:  2012-11-13       Impact factor: 3.534
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