Literature DB >> 1634357

A new alpha chain variant, Hb Turriff [alpha 99(G6)Lys----Glu]: the interference of abnormal hemoglobins in Hb A1c determination.

J V Langdown1, R J Davidson, D Williamson.   

Abstract

Hb Turriff is a new hemoglobin variant which we have identified in a diabetic individual. During the determination of Hb A1c by high performance liquid chromatography, an inappropriately elevated result was found to be due to the abnormal hemoglobin chromatographing with the Hb A1c fraction. This new hemoglobin variant, Hb Turriff [alpha 99(G6)Lys----Glu], is not associated with any hematological disturbance, and family investigations indicate that it has arisen as a de novo mutation.

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Year:  1992        PMID： 1634357     DOI： 10.3109/03630269209005671

Source DB:  PubMed          Journal:  Hemoglobin        ISSN： 0363-0269            Impact factor:   0.849


  4 in total

1.  A rare haemoglobin variant (Hb Phnom Penh) manifesting as a falsely high haemoglobin A1c value on ion-exchange chromatography.

Authors:  Chi-Fen Chen; Yen-Kuang Tai
Journal:  Singapore Med J       Date:  2014-08       Impact factor: 1.858

Review 2.  Hemoglobin variants: biochemical properties and clinical correlates.

Authors:  Christopher S Thom; Claire F Dickson; David A Gell; Mitchell J Weiss
Journal:  Cold Spring Harb Perspect Med       Date:  2013-03-01       Impact factor: 6.915

Review 3.  Hemoglobin variants recently detected in Austria.

Authors:  W J Schnedl; E C Reisinger; R W Lipp; G J Krejs; P Hopmeier
Journal:  Ann Hematol       Date:  1995-10       Impact factor: 3.673

4.  Analysis of human alpha globin gene mutations that impair binding to the alpha hemoglobin stabilizing protein.

Authors:  Xiang Yu; Todd L Mollan; Andrew Butler; Andrew J Gow; John S Olson; Mitchell J Weiss
Journal:  Blood       Date:  2009-04-06       Impact factor: 22.113
  4 in total

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