Literature DB >> 16343564

A triterpenoid saponin possessing antileishmanial activity from the leaves of Careya arborea.

Debayan Mandal1, Nilendu Panda, Shrabanti Kumar, Sukdeb Banerjee, Nirup B Mandal, Niranjan P Sahu.   

Abstract

Bioguided-fractionation of the methanol extract of the leaves of Careya arborea led to isolation of a triterpenoid saponin, designated arborenin, and characterized as 3-O-beta-D-glucopyranosyl(1-->2)-beta-D-glucopyranosyl-2 alpha,3beta-dihydroxy-taraxast-20-en-28-oic acid (1), together with desacylescin III (2). The structures were determined on the basis of extensive 2D NMR spectroscopic analysis. The saponin showed in vitro antileishmanial activity against Leishmania donovani (strain AG 83).

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 16343564     DOI: 10.1016/j.phytochem.2005.10.028

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  4 in total

1.  Antiplasmodial activity of novel stilbene derivatives isolated from Parthenocissus tricuspidata from South Korea.

Authors:  Il Hong Son; Ill-Min Chung; Sun-Joo Lee; Hyung-In Moon
Journal:  Parasitol Res       Date:  2007-01-09       Impact factor: 2.289

2.  Inhibitory effects of Thai plants beta-glycosides on Trichomonas vaginalis.

Authors:  Dumrongkiet Arthan; Somphong Sithiprom; Kanthinich Thima; Chutima Limmatvatirat; Porntip Chavalitshewinkoon-Petmitr; Jisnuson Svasti
Journal:  Parasitol Res       Date:  2008-05-08       Impact factor: 2.289

3.  An investigation of the antileishmanial properties of semi-synthetic saponins.

Authors:  Orlagh Anderson; Joseph Beckett; Carla C Briggs; Liam A Natrass; Charles F Cranston; Elizabeth J Wilkinson; Jack H Owen; Rhodri Mir Williams; Angelos Loukaidis; Marc E Bouillon; Deiniol Pritchard; Martina Lahmann; Mark S Baird; Paul W Denny
Journal:  RSC Med Chem       Date:  2020-06-09

4.  Antimalarial activity of a cis-terpenone.

Authors:  D C Ghislaine Mayer; Maimuna Bruce; Olga Kochurova; Jennifer K Stewart; Qibing Zhou
Journal:  Malar J       Date:  2009-06-25       Impact factor: 2.979

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.