Literature DB >> 16340029

A case of tetramine poisoning: a lethal rodenticide.

W T Poon1, K Chan, M H Lo, K K Yip, T Lee, A Y W Chan.   

Abstract

We report a fatal case of suicide presenting with convulsions and subsequently multi-organ failure. Rodenticide poisoning was not suspected until the next day when tetramine was detected in the patient's blood, urine, and food residues. Tetramine is a potent rodenticide with a rapid action and high mortality. The poison has been banned worldwide but is still readily available in Mainland China. Outbreaks of poisoning are reported frequently and doctors should be alert for this lethal toxin.

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Year:  2005        PMID: 16340029

Source DB:  PubMed          Journal:  Hong Kong Med J        ISSN: 1024-2708            Impact factor:   2.227


  5 in total

1.  Combined diazepam and MK-801 therapy provides synergistic protection from tetramethylenedisulfotetramine-induced tonic-clonic seizures and lethality in mice.

Authors:  Michael P Shakarjian; Mahil S Ali; Jana Velíšková; Patric K Stanton; Diane E Heck; Libor Velíšek
Journal:  Neurotoxicology       Date:  2015-03-14       Impact factor: 4.294

2.  Differential antagonism of tetramethylenedisulfotetramine-induced seizures by agents acting at NMDA and GABA(A) receptors.

Authors:  Michael P Shakarjian; Jana Velíšková; Patric K Stanton; Libor Velíšek
Journal:  Toxicol Appl Pharmacol       Date:  2012-09-27       Impact factor: 4.219

3.  Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication.

Authors:  Stephen T Vito; Adam T Austin; Christopher N Banks; Bora Inceoglu; Donald A Bruun; Dorota Zolkowska; Daniel J Tancredi; Michael A Rogawski; Bruce D Hammock; Pamela J Lein
Journal:  Toxicol Appl Pharmacol       Date:  2014-10-14       Impact factor: 4.219

4.  Developmental and sex differences in tetramethylenedisulfotetramine (TMDT)-induced syndrome in rats.

Authors:  Marcela Lauková; Jana Velíšková; Libor Velíšek; Michael P Shakarjian
Journal:  Dev Neurobiol       Date:  2018-02-14       Impact factor: 3.964

5.  Lessons learned from poisoning cases caused by 2 illegal rodenticides: Tetramine and fluoroacetamide.

Authors:  Rongshuai Wang; Luo Zhuo; Yunyun Wang; Liang Ren; Qian Liu; Liang Liu
Journal:  Medicine (Baltimore)       Date:  2016-10       Impact factor: 1.889

  5 in total

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