Literature DB >> 16339280

Multiple Alignment of protein structures and sequences for VMD.

John Eargle1, Dan Wright, Zaida Luthey-Schulten.   

Abstract

Multiple Alignment is a new interface for performing and analyzing multiple protein structure alignments. It enables viewing levels of sequence and structure similarity on the aligned structures and performing a variety of evolutionary and bioinformatic tasks, including the construction of structure-based phylogenetic trees and minimal basis sets of structures that best represent the topology of the phylogenetic tree. It is implemented as a plugin for VMD (Visual Molecular Dynamics), which is distributed by the NIH Resource for Macromolecular Modeling and Bioinformatics at the University of Illinois.

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Year:  2005        PMID: 16339280     DOI: 10.1093/bioinformatics/bti825

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  45 in total

1.  Simulation on the structure of pig liver esterase.

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2.  Structure of the ribosomal interacting GTPase YjeQ from the enterobacterial species Salmonella typhimurium.

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3.  Computational modeling of structurally conserved cancer mutations in the RET and MET kinases: the impact on protein structure, dynamics, and stability.

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4.  Molecular mechanisms underlying deoxy-ADP.Pi activation of pre-powerstroke myosin.

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Journal:  Protein Sci       Date:  2017-03-21       Impact factor: 6.725

Review 5.  Ligand-binding PAS domains in a genomic, cellular, and structural context.

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Journal:  Annu Rev Microbiol       Date:  2011       Impact factor: 15.500

6.  Mitochondrial Methylenetetrahydrofolate Dehydrogenase (MTHFD2) Overexpression Is Associated with Tumor Cell Proliferation and Is a Novel Target for Drug Development.

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Journal:  Mol Cancer Res       Date:  2015-06-22       Impact factor: 5.852

7.  Functional analysis of a mosquito short-chain dehydrogenase cluster.

Authors:  Jaime G Mayoral; Kate T Leonard; Marcela Nouzova; Fernando G Noriega; Lucas A Defelipe; Adrian G Turjanski
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8.  Juvenile hormone synthesis: "esterify then epoxidize" or "epoxidize then esterify"? Insights from the structural characterization of juvenile hormone acid methyltransferase.

Authors:  L A Defelipe; E Dolghih; A E Roitberg; M Nouzova; J G Mayoral; F G Noriega; A G Turjanski
Journal:  Insect Biochem Mol Biol       Date:  2010-12-31       Impact factor: 4.714

9.  Sensitivity in Binding Free Energies Due to Protein Reorganization.

Authors:  Nathan M Lim; Lingle Wang; Robert Abel; David L Mobley
Journal:  J Chem Theory Comput       Date:  2016-08-16       Impact factor: 6.006

10.  Hierarchical modeling of activation mechanisms in the ABL and EGFR kinase domains: thermodynamic and mechanistic catalysts of kinase activation by cancer mutations.

Authors:  Anshuman Dixit; Gennady M Verkhivker
Journal:  PLoS Comput Biol       Date:  2009-08-28       Impact factor: 4.475

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