Literature DB >> 16338854

Current ideas about applications of heat shock proteins in vaccine design and immunotherapy.

X-Y- Wang1, Y Li, G Yang, J R Subjeck.   

Abstract

Heat shock proteins (HSPs), as molecular chaperones, perform critical functions in maintaining cell homeostasis. Certain HSPs in extra-cellular milieu are capable of modulating innate and adaptive immunity due to their ability to chaperone polypeptides and to interact with the host's immune system, particularly professional antigen presenting cells (APCs). This review summarizes the immunomodulating functions of HSPs and their potential applications in cancer immunotherapy.

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Year:  2005        PMID： 16338854     DOI： 10.1080/02656730500226407

Source DB:  PubMed          Journal:  Int J Hyperthermia        ISSN： 0265-6736            Impact factor:   3.914


  8 in total

1.  Spectroscopic and thermodynamic properties of recombinant heat shock protein A6 from Camelus dromedarius.

Authors:  Ajamaluddin Malik; Abuzar Haroon; Haseeb Jagirdar; Abdulrahman M Alsenaidy; Mohamed Elrobh; Wajahatullah Khan; Mohammed S Alanazi; Mohammad D Bazzi
Journal:  Eur Biophys J       Date:  2014-11-14       Impact factor: 1.733

2.  Unique peptide substrate binding properties of 110-kDa heat-shock protein (Hsp110) determine its distinct chaperone activity.

Authors:  Xinping Xu; Evans Boateng Sarbeng; Christina Vorvis; Divya Prasanna Kumar; Lei Zhou; Qinglian Liu
Journal:  J Biol Chem       Date:  2011-12-08       Impact factor: 5.157

3.  Kadota Fund International Forum 2004. Application of thermal stress for the improvement of health, 15-18 June 2004, Awaji Yumebutai International Conference Center, Awaji Island, Hyogo, Japan. Final report.

Authors:  Tsutomu Sugahara; J van der Zee; Harm H Kampinga; Zeliko Vujaskovic; Motoharu Kondo; Takeo Ohnishi; Gloria Li; Heon J Park; Dennis B Leeper; Valentina Ostapenko; Elizabeth A Repasky; Masami Watanabe; Chang W Song
Journal:  Int J Hyperthermia       Date:  2008-03       Impact factor: 3.914

4.  Tumour secreted grp170 chaperones full-length protein substrates and induces an adaptive anti-tumour immune response in vivo.

Authors:  Hilal Arnouk; Evan R Zynda; Xiang-Yang Wang; Bonnie L Hylander; Masoud H Manjili; Elizabeth A Repasky; John R Subjeck; A Latif Kazim
Journal:  Int J Hyperthermia       Date:  2010       Impact factor: 3.914

5.  Heat-shock protein vaccines as active immunotherapy against human gliomas.

Authors:  Isaac Yang; Seunggu Han; Andrew T Parsa
Journal:  Expert Rev Anticancer Ther       Date:  2009-11       Impact factor: 4.512

6.  Molecular cloning and characterization of cDNA encoding a putative stress-induced heat-shock protein from Camelus dromedarius.

Authors:  Mohamed S Elrobh; Mohammad S Alanazi; Wajahatullah Khan; Zainularifeen Abduljaleel; Abdullah Al-Amri; Mohammad D Bazzi
Journal:  Int J Mol Sci       Date:  2011-06-27       Impact factor: 5.923

7.  Optimization of expression and purification of HSPA6 protein from Camelus dromedarius in E. coli.

Authors:  Ajamaluddin Malik; Abdulrahman M Alsenaidy; Mohamed Elrobh; Wajahatullah Khan; Mohammed S Alanazi; Mohammad D Bazzi
Journal:  Saudi J Biol Sci       Date:  2015-05-04       Impact factor: 4.219

8.  Gene medicine for cancer treatment: commercially available medicine and accumulated clinical data in China.

Authors:  Guangyu Ma; Hideaki Shimada; Kenzo Hiroshima; Yuji Tada; Nobuo Suzuki; Masatoshi Tagawa
Journal:  Drug Des Devel Ther       Date:  2009-02-06       Impact factor: 4.162
  8 in total

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