Literature DB >> 16337189

Angiogenesis in the mouse retina: a model system for experimental manipulation.

Akiyoshi Uemura1, Sentaro Kusuhara, Hideto Katsuta, Shin-Ichi Nishikawa.   

Abstract

The vascular system of the mouse retina provides a useful model for analyzing the molecular and cellular mechanisms regulating angiogenesis because (1) hierarchical vascular networks are newly formed only after birth, (2) the cellular components involved in angiogenesis are well characterized, and (3) all the processes are accessible for monitoring and manipulation. In this article, we present an overview of our current understanding of the process of retinal angiogenesis and describe a number of methodologies applicable to experimental manipulation of the retinal vascular system.

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Year:  2005        PMID: 16337189     DOI: 10.1016/j.yexcr.2005.10.030

Source DB:  PubMed          Journal:  Exp Cell Res        ISSN: 0014-4827            Impact factor:   3.905


  39 in total

1.  Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ₃.

Authors:  Sribalaji Lakshmikanthan; Magdalena Sobczak; Changzoon Chun; Angela Henschel; Jillian Dargatz; Ramani Ramchandran; Magdalena Chrzanowska-Wodnicka
Journal:  Blood       Date:  2011-06-02       Impact factor: 22.113

Review 2.  Tips, stalks, tubes: notch-mediated cell fate determination and mechanisms of tubulogenesis during angiogenesis.

Authors:  Jennifer J Tung; Ian W Tattersall; Jan Kitajewski
Journal:  Cold Spring Harb Perspect Med       Date:  2012-02       Impact factor: 6.915

Review 3.  Notch signaling in ocular vasculature development and diseases.

Authors:  Guo-Rui Dou; Lin Wang; Yu-Sheng Wang; Hua Han
Journal:  Mol Med       Date:  2012-02-10       Impact factor: 6.354

4.  Altered vascular expression of EphrinB2 and EphB4 in a model of oxygen-induced retinopathy.

Authors:  Michael H Davies; Andrew J Stempel; Kristin E Hubert; Michael R Powers
Journal:  Dev Dyn       Date:  2010-06       Impact factor: 3.780

5.  VEGF and endothelial guidance in angiogenic sprouting.

Authors:  Holger Gerhardt
Journal:  Organogenesis       Date:  2008-10       Impact factor: 2.500

6.  Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown.

Authors:  Shuntaro Ogura; Kaori Kurata; Yuki Hattori; Hiroshi Takase; Toshina Ishiguro-Oonuma; Yoonha Hwang; Soyeon Ahn; Inwon Park; Wataru Ikeda; Sentaro Kusuhara; Yoko Fukushima; Hiromi Nara; Hideto Sakai; Takashi Fujiwara; Jun Matsushita; Masatsugu Ema; Masanori Hirashima; Takashi Minami; Masabumi Shibuya; Nobuyuki Takakura; Pilhan Kim; Takaki Miyata; Yuichiro Ogura; Akiyoshi Uemura
Journal:  JCI Insight       Date:  2017-02-09

7.  Interaction of kindlin-2 with integrin β3 promotes outside-in signaling responses by the αVβ3 vitronectin receptor.

Authors:  Zhongji Liao; Hisashi Kato; Manjula Pandey; Joseph M Cantor; Ararat J Ablooglu; Mark H Ginsberg; Sanford J Shattil
Journal:  Blood       Date:  2015-01-13       Impact factor: 22.113

8.  Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice.

Authors:  Magdalena Chrzanowska-Wodnicka; Anna E Kraus; Daniel Gale; Gilbert C White; Jillian Vansluys
Journal:  Blood       Date:  2007-11-09       Impact factor: 22.113

9.  Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis.

Authors:  Amir Rattner; Huimin Yu; John Williams; Philip M Smallwood; Jeremy Nathans
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-16       Impact factor: 11.205

10.  Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.

Authors:  Christopher A Jones; Nyall R London; Haoyu Chen; Kye Won Park; Dominique Sauvaget; Rebecca A Stockton; Joshua D Wythe; Wonhee Suh; Frederic Larrieu-Lahargue; Yoh-Suke Mukouyama; Per Lindblom; Pankaj Seth; Antonio Frias; Naoyuki Nishiya; Mark H Ginsberg; Holger Gerhardt; Kang Zhang; Dean Y Li
Journal:  Nat Med       Date:  2008-03-16       Impact factor: 53.440

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