| Literature DB >> 16337119 |
Radim Nencka1, Ivan Votruba, Hubert Hrebabecký, Eva Tloust'ová, Kveta Horská, Milena Masojídková, Antonín Holý.
Abstract
We report on a series of novel 5,6-disubstituted uracils with significant inhibitory activity against human and Escherichia coli thymidine phosphorylases. Bis-uracil conjugates were identified as the most potent inhibitors of TPs in this study.Entities:
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Year: 2005 PMID： 16337119 DOI： 10.1016/j.bmcl.2005.11.050
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823