Literature DB >> 16337073

Serum ionized magnesium during magnesium sulfate administration for preterm labor and preeclampsia.

Mayumi Yoshida1, Yoshio Matsuda, Yoshika Akizawa, Erina Ono, Hiroaki Ohta.   

Abstract

OBJECTIVE: The purpose of this study is to estimate the relations between ionized and total Mg levels during MgSO4 administration in patients with preterm labor and preeclampsia.
METHODS: Forty-three pregnant patients who were candidates for MgSO4 were studied (preterm labor, 27; preeclampsia, 16). The administration method was intravenous injection of MgSO4 4 g over 30 min followed by 1-2 g/h. Ionized Mg was measured by the selective ion electrode method at bedside, and compared it with total Mg levels.
RESULTS: Significant correlation was existed between levels of ionized and total Mg throughout therapy for both preterm labor (ionized Mg=0.19 x total Mg+0.19; r=0.61, p<0.001) and preeclampsia (ionized Mg=0.20 x total Mg+0.14; r=0.60, p<0.001).
CONCLUSION: There are correlations between ionized and total Mg levels during administration of MgSO4 for both preterm labor and preeclampsia.

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Year:  2005        PMID: 16337073     DOI: 10.1016/j.ejogrb.2005.10.036

Source DB:  PubMed          Journal:  Eur J Obstet Gynecol Reprod Biol        ISSN: 0301-2115            Impact factor:   2.435


  4 in total

1.  Feasibility of short-term infusion of magnesium sulfate in pediatric patients with status asthmaticus.

Authors:  Jose Irazuzta; Tosha Egelund; Sarah K Wassil; Christian Hampp
Journal:  J Pediatr Pharmacol Ther       Date:  2012-04

2.  High-dose magnesium sulfate infusion protocol for status asthmaticus: a safety and pharmacokinetics cohort study.

Authors:  Tosha A Egelund; Sarah K Wassil; Elisa M Edwards; Stephan Linden; Jose E Irazuzta
Journal:  Intensive Care Med       Date:  2012-11-06       Impact factor: 17.440

Review 3.  Clinical pharmacokinetic properties of magnesium sulphate in women with pre-eclampsia and eclampsia.

Authors:  B O Okusanya; O T Oladapo; Q Long; P Lumbiganon; G Carroli; Z Qureshi; L Duley; J P Souza; A M Gülmezoglu
Journal:  BJOG       Date:  2015-11-24       Impact factor: 6.531

4.  Total and ionized serum magnesium and calcium levels during magnesium sulfate administration for preterm labor.

Authors:  Won Hee Kim; Yoon Ha Kim; Yuna An; Jong Ho Moon; Eun Ji Noh; Jong Woon Kim
Journal:  Obstet Gynecol Sci       Date:  2017-12-12
  4 in total

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