Literature DB >> 16335954

Genomic and proteomic analysis of mammary tumors arising in transgenic mice.

Lu Xie1, Baogang J Xu, Agnieszka E Gorska, Yu Shyr, Sarah A Schwartz, Nikki Cheng, Shawn Levy, Brian Bierie, Richard M Caprioli, Harold L Moses.   

Abstract

Transforming growth factor-beta (TGF-beta) is the prototype of a large family of signaling molecules. TGF-beta signaling profoundly influences tumor development as demonstrated in several engineered mouse models. The present study was designed to identify differences by cDNA microarray and MALDI-TOF MS analyses in mammary carcinomas with and without TGF-beta signaling. The results demonstrate a significant potential for combination of profiling technologies to further understand the molecular mechanisms of breast cancer.

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Year:  2005        PMID： 16335954     DOI： 10.1021/pr050214l

Source DB:  PubMed          Journal:  J Proteome Res        ISSN： 1535-3893            Impact factor:   4.466


  3 in total

1.  Molecular analysis of tumor margins by MALDI mass spectrometry in renal carcinoma.

Authors:  Stacey R Oppenheimer; Deming Mi; Melinda E Sanders; Richard M Caprioli
Journal:  J Proteome Res       Date:  2010-05-07       Impact factor: 4.466

2.  Co-registration of multi-modality imaging allows for comprehensive analysis of tumor-induced bone disease.

Authors:  Erin H Seeley; Kevin J Wilson; Thomas E Yankeelov; Rachelle W Johnson; John C Gore; Richard M Caprioli; Lynn M Matrisian; Julie A Sterling
Journal:  Bone       Date:  2014-01-30       Impact factor: 4.398

Review 3.  Recent advances in single-cell MALDI mass spectrometry imaging and potential clinical impact.

Authors:  Kristin J Boggio; Emmanuel Obasuyi; Ken Sugino; Sacha B Nelson; Nathalie Yr Agar; Jeffrey N Agar
Journal:  Expert Rev Proteomics       Date:  2011-10       Impact factor: 3.940
  3 in total

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