| Literature DB >> 1633194 |
K Yoshikawa1, T Noguti, M Tsujimura, H Koga, T Yasukochi, T Horiuchi, M Go.
Abstract
During investigations of the structural character of a mutant P-450cam where Glu-286 is replaced with lysine, we obtained evidence of a hydrogen bond network between helix K and the heme group via helix L of P-450cam. This mutant protein loses the ability to maintain the heme group in a proper position, possibly due to a break in the hydrogen bond network.Entities:
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Year: 1992 PMID： 1633194 DOI： 10.1016/0167-4838(92)90124-v
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002