OBJECTIVE: To evaluate the relationship between bed-wetting and various developmental milestones in a large and representative sample of young children. DESIGN: A randomized 3-level stratified survey design. SETTING: Data were collected by questionnaires, and interviews were scheduled at home with the mother. PARTICIPANTS: A representative sample of children born from 1997 to 1998 in Quebec. A complete set of data on bed-wetting was obtained for 1666 children at the ages of 29, 41, and 53 months. MAIN OUTCOME MEASURES: Percentage of children who bed-wet and developmental factors associated with bed-wetting. RESULTS: Approximately 10% of the children were bed-wetting at the age of 53 months. Bed-wetting cessation occurred for most children studied between the ages of 29 and 41 months. Motor skills were achieved by fewer boys who bed-wet compared with boys who did not (had sat up without support for 10 minutes at 5 months, P = .05; and had started crawling at 5 months, P<.01). More girls who bed-wet were prematurely born and had hyperactivity and inattention (P<.01 for all) compared with those who did not. Language milestones were achieved by fewer children who bed-wet compared with those who did not (boys: P = .04; girls: P = .02). No between-group difference was found for physical growth and sleep variables. CONCLUSIONS: These findings show an association between bed-wetting and developmental milestones in early childhood. This study supports that bed-wetting could be indicative of a possible delay in the development of the central nervous system and could act as a noticeable indicator for parents and pediatricians.
RCT Entities:
OBJECTIVE: To evaluate the relationship between bed-wetting and various developmental milestones in a large and representative sample of young children. DESIGN: A randomized 3-level stratified survey design. SETTING: Data were collected by questionnaires, and interviews were scheduled at home with the mother. PARTICIPANTS: A representative sample of children born from 1997 to 1998 in Quebec. A complete set of data on bed-wetting was obtained for 1666 children at the ages of 29, 41, and 53 months. MAIN OUTCOME MEASURES: Percentage of children who bed-wet and developmental factors associated with bed-wetting. RESULTS: Approximately 10% of the children were bed-wetting at the age of 53 months. Bed-wetting cessation occurred for most children studied between the ages of 29 and 41 months. Motor skills were achieved by fewer boys who bed-wet compared with boys who did not (had sat up without support for 10 minutes at 5 months, P = .05; and had started crawling at 5 months, P<.01). More girls who bed-wet were prematurely born and had hyperactivity and inattention (P<.01 for all) compared with those who did not. Language milestones were achieved by fewer children who bed-wet compared with those who did not (boys: P = .04; girls: P = .02). No between-group difference was found for physical growth and sleep variables. CONCLUSIONS: These findings show an association between bed-wetting and developmental milestones in early childhood. This study supports that bed-wetting could be indicative of a possible delay in the development of the central nervous system and could act as a noticeable indicator for parents and pediatricians.
Authors: Thomas M Hyde; Amy Deep-Soboslay; Bianca Iglesias; Joseph H Callicott; James M Gold; Andreas Meyer-Lindenberg; Robyn A Honea; Llewellyn B Bigelow; Michael F Egan; Esther M Emsellem; Daniel R Weinberger Journal: Brain Date: 2008-07-31 Impact factor: 13.501
Authors: Suresh Kotagal; Cynthia D Nichols; Madeleine M Grigg-Damberger; Carole L Marcus; Manisha B Witmans; Valerie G Kirk; Lynn A D'Andrea; Timothy F Hoban Journal: Sleep Date: 2012-11-01 Impact factor: 5.849
Authors: Shaogen Zhong; Lichi Zhang; Mengxing Wang; Jiayao Shen; Yi Mao; Xiaoxia Du; Jun Ma Journal: Front Psychiatry Date: 2022-08-22 Impact factor: 5.435