Literature DB >> 16330451

Variability of quantitative polymerase chain reaction detection of the bcl-2-IgH translocation in an international multicenter study.

Angela J Darby, Stuart Lanham, Pierre Soubeyran, Peter W M Johnson.   

Abstract

The t(14;18)(q32;q21) chromosomal translocation is closely associated with follicular lymphoma. Polymerase chain reaction (PCR) analysis has high sensitivity and is used to assess responses to therapy. Quantification of translocation-bearing cells is a possible advantage of real-time PCR over conventional PCR. A collaborative study comparing results from 12 international laboratories is reported.

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Year:  2005        PMID: 16330451

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


  2 in total

1.  Demonstration of array-based analysis for highly multiplexed PCR assays application to detection of IGH@-BCL2 translocations in FFPE follicular lymphoma specimens.

Authors:  Janice M Spence; Paul G Rothberg; Nancy Wang; W Richard Burack
Journal:  J Mol Diagn       Date:  2011-05       Impact factor: 5.568

2.  Prevalence and frequency of circulating t(14;18)-MBR translocation carrying cells in healthy individuals.

Authors:  Frank Schüler; Lars Dölken; Carsten Hirt; Thomas Kiefer; Tobias Berg; Gerhard Fusch; K Weitmann; W Hoffmann; Christoph Fusch; Siegfried Janz; Charles S Rabkin; Gottfried Dölken
Journal:  Int J Cancer       Date:  2009-02-15       Impact factor: 7.396

  2 in total

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