| Literature DB >> 16330129 |
Mathieu Sassatelli1, Fadoua Bouchikhi, Samir Messaoudi, Fabrice Anizon, Eric Debiton, Chantal Barthomeuf, Michelle Prudhomme, Pascale Moreau.
Abstract
In the course of structure-activity relationship studies, diversely substituted 1-(beta-D-glucopyranosyl)-isoindigo derivatives were prepared from commercially available indolines. Their antiproliferative activities were evaluated toward a panel of human solid cancer cell lines (PC 3, DLD-1, MCF-7, M4Beu, A549, PA 1), a murine cell line (L929) and a human fibroblast primary culture to get an insight into the substitution pattern required for the best biological potencies.Entities:
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Year: 2005 PMID： 16330129 DOI： 10.1016/j.ejmech.2005.10.004
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514