Literature DB >> 1632962

Appearance of phloridzin-sensitive glucose transport is not controlled at mRNA level in rabbit jejunal enterocytes.

M W Smith1, A Turvey, T C Freeman.   

Abstract

Glucose uptake by rabbit intestine has been shown to be confined to the upper two-thirds of jejunal villi. Inhibition by phloridzin shows most of this transport to take place through the Na(+)-glucose linked transporter (SGLT1). Parallel measurements on the other hand show SGLT1 mRNA expression to increase rapidly as enterocytes reach the crypt-villus junction. Levels of SGLT1 mRNA then remain elevated in all villus enterocytes. These results provide direct evidence that SGLT1-mediated glucose transport is subject to post-transcriptional control.

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Year:  1992        PMID： 1632962     DOI： 10.1113/expphysiol.1992.sp003616

Source DB:  PubMed          Journal:  Exp Physiol        ISSN： 0958-0670            Impact factor:   2.969


  10 in total

1.  Apical Na+-D-glucose cotransporter 1 (SGLT1) activity and protein abundance are expressed along the jejunal crypt-villus axis in the neonatal pig.

Authors:  Chengbo Yang; David M Albin; Zirong Wang; Barbara Stoll; Dale Lackeyram; Kendall C Swanson; Yulong Yin; Kelly A Tappenden; Yoshinori Mine; Rickey Y Yada; Douglas G Burrin; Ming Z Fan
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-10-28       Impact factor: 4.052

Review 2.  Dietary and developmental regulation of intestinal sugar transport.

Authors:  R P Ferraris
Journal:  Biochem J       Date:  2001-12-01       Impact factor: 3.857

3.  H+/di-tripeptide transporter (PepT1) expression in the rabbit intestine.

Authors:  T C Freeman; B S Bentsen; D T Thwaites; N L Simmons
Journal:  Pflugers Arch       Date:  1995-07       Impact factor: 3.657

Review 4.  Function and presumed molecular structure of Na(+)-D-glucose cotransport systems.

Authors:  H Koepsell; J Spangenberg
Journal:  J Membr Biol       Date:  1994-02       Impact factor: 1.843

5.  Selective regulation of epithelial gene expression in rabbit Peyer's patch tissue.

Authors:  T C Savidge; M W Smith; S Mayel-Afshar; A J Collins; T C Freeman
Journal:  Pflugers Arch       Date:  1994-10       Impact factor: 3.657

6.  Genetic regulation of enterocyte function: a quantitative in situ hybridisation study of lactase-phlorizin hydrolase and Na(+)-glucose cotransporter mRNAs in rabbit small intestine.

Authors:  T C Freeman; A J Collins; R P Heavens; D R Tivey
Journal:  Pflugers Arch       Date:  1993-03       Impact factor: 3.657

Review 7.  Mammalian ion-coupled solute transporters.

Authors:  M A Hediger; Y Kanai; G You; S Nussberger
Journal:  J Physiol       Date:  1995-01       Impact factor: 5.182

8.  The effects of streptozotocin diabetes on sodium-glucose transporter (SGLT1) expression and function in rat jejunal and ileal villus-attached enterocytes.

Authors:  E S Debnam; M W Smith; P A Sharp; S K Srai; A Turvey; S J Keable
Journal:  Pflugers Arch       Date:  1995-06       Impact factor: 3.657

9.  Crypt/villus site of substrate-dependent regulation of mouse intestinal glucose transporters.

Authors:  R P Ferraris; J M Diamond
Journal:  Proc Natl Acad Sci U S A       Date:  1993-06-15       Impact factor: 11.205

Review 10.  H+-coupled nutrient, micronutrient and drug transporters in the mammalian small intestine.

Authors:  David T Thwaites; Catriona M H Anderson
Journal:  Exp Physiol       Date:  2007-04-27       Impact factor: 2.969
  10 in total

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