Literature DB >> 16328685

Use of semiflexible applicators for radiofrequency ablation of liver tumors.

G Gaffke1, B Gebauer, F D Knollmann, T Helmberger, J Ricke, H Oettle, R Felix, C Stroszczynski.   

Abstract

PURPOSE: To evaluate the feasibility and potential advantages of the radiofrequency ablation of liver tumors using new MRI-compatible semiflexible applicators in a closed-bore high-field MRI scanner.
METHODS: We treated 8 patients with 12 malignant liver tumors of different origin (5 colorectal carcinoma, 2 cholangiocellular carcinoma, 1 breast cancer) under MRI guidance. Radiofrequency ablation (RFA) was performed using 5 cm Rita Starburst Semi-Flex applicators (Rita Medical Systems, Milwaukee, WI, USA) which are suitable for MR- and CT-guided interventions and a 150 W RF generator. All interventions were performed in a closed-bore 1.5 T high-field MRI scanner for MRI-guided RFA using fast T1-weighted gradient echo sequences and T2-weighted ultra-turbo spin echo sequences. Control and follow-up MRI examinations were performed on the next day, at 6 weeks, and every 3 months after RFA. Control MRI were performed as double-contrast MRI examinations (enhancement with iron oxide and gadopentetate dimeglumine). All interventions were performed with the patient under local anesthesia and analgo-sedation.
RESULTS: The mean diameter of the treated hepatic tumors was 2.4 cm (+/-0.6 cm, range 1.0-3.2 cm). The mean diameter of induced necrosis was 3.1 cm (+/-0.4 cm). We achieved complete ablation in all patients. Follow-up examinations over a duration of 7 months (+/-1.3 months, range 4-9 month) showed a local control rate of 100% in this group of patients. All interventions were performed without major complications; only 2 subcapsular hematomas were documented.
CONCLUSION: RFA of liver tumors using semiflexible applicators in closed-bore 1.5 T scanner systems is feasible. These applicators might simplify the RFA of liver tumors under MRI control. The stiff distal part of the applicator facilitates its repositioning.

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Year:  2006        PMID: 16328685     DOI: 10.1007/s00270-005-0052-x

Source DB:  PubMed          Journal:  Cardiovasc Intervent Radiol        ISSN: 0174-1551            Impact factor:   2.740


  2 in total

1.  Laser-induced thermotherapy (LITT)--evaluation of a miniaturised applicator and implementation in a 1.0-T high-field open MRI applying a porcine liver model.

Authors:  Florian Streitparth; Gesine Knobloch; Dirk Balmert; Sascha Chopra; J Rump; Uta Wonneberger; Carsten Philipp; Bernd Hamm; Ulf Teichgräber
Journal:  Eur Radiol       Date:  2010-06-08       Impact factor: 5.315

2.  MR-guided radiofrequency ablation using a wide-bore 1.5-T MR system: clinical results of 213 treated liver lesions.

Authors:  Hansjörg Rempp; Lorenz Waibel; Rüdiger Hoffmann; Claus D Claussen; Philippe L Pereira; Stephan Clasen
Journal:  Eur Radiol       Date:  2012-04-18       Impact factor: 5.315

  2 in total

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