BACKGROUND: The intraoperative assessment of lymph node status is important when performing limited surgery in gastric cancer patients. Currently available techniques for this assessment are frozen section, imprint cytology, and other molecular methods; most current studies use the frozen-section method. In the present study, we focused on the accuracy and feasibility of imprint cytology as a tool to assess lymph node status intraoperatively in gastric cancer surgery. METHODS: Between April 2001 and March 2003, we performed imprint cytology of the sentinel nodes in 260 consecutive patients. After review by an experienced cytopathologist, the sensitivity, specificity, and overall accuracy of the method were determined. RESULTS: The time required for the intraoperative imprint cytology was 8 min, and the sensitivity, specificity, and overall accuracy were 52.2%, 88.8%, and 73.8%, respectively. CONCLUSION: Imprint cytology could be a useful technique for the assessment of lymph node status intraoperatively if the sensitivity and specificity can be improved to an acceptable level.
BACKGROUND: The intraoperative assessment of lymph node status is important when performing limited surgery in gastric cancerpatients. Currently available techniques for this assessment are frozen section, imprint cytology, and other molecular methods; most current studies use the frozen-section method. In the present study, we focused on the accuracy and feasibility of imprint cytology as a tool to assess lymph node status intraoperatively in gastric cancer surgery. METHODS: Between April 2001 and March 2003, we performed imprint cytology of the sentinel nodes in 260 consecutive patients. After review by an experienced cytopathologist, the sensitivity, specificity, and overall accuracy of the method were determined. RESULTS: The time required for the intraoperative imprint cytology was 8 min, and the sensitivity, specificity, and overall accuracy were 52.2%, 88.8%, and 73.8%, respectively. CONCLUSION: Imprint cytology could be a useful technique for the assessment of lymph node status intraoperatively if the sensitivity and specificity can be improved to an acceptable level.
Authors: Charles Cox; Barbara Centeno; Dan Dickson; John Clark; Santo Nicosia; Elisabeth Dupont; Harvey Greenberg; Nicholas Stowell; Laura White; Jayesh Patel; Ben Furman; Alan Cantor; Ardeshir Hakam; Nazeel Ahmad; Nils Diaz; Jeff King Journal: Cancer Date: 2005-02-25 Impact factor: 6.860
Authors: M Hiratsuka; I Miyashiro; O Ishikawa; H Furukawa; K Motomura; H Ohigashi; M Kameyama; Y Sasaki; T Kabuto; S Ishiguro; S Imaoka; H Koyama Journal: Surgery Date: 2001-03 Impact factor: 3.982
Authors: T Kosaka; N Ueshige; J Sugaya; Y Nakano; T Akiyama; F Tomita; H Saito; I Kita; S Takashima Journal: Surg Today Date: 1999 Impact factor: 2.549