Literature DB >> 16328212

[Questionnaire on crossover renal transplantations in Germany].

A Hamza1, H Loertzer, A Wicht, O Rettkowski, E Koch, P Fornara.   

Abstract

Due to increasingly better long-term survival rates with dialysis the number of patients with renal failure constantly increases by 4% annually worldwide. Despite great progress in operative and perioperative management as well as improved immunosuppressive drugs, kidney transplantation still faces two major problems. First of all there is a huge deficit of donor organs and secondly the long-term results of the kidney grafts must be improved. One way to relieve this tense situation may be live kidney donation. In many countries not participating in Eurotransplant, especially the United States and Scandinavia, live kidney donation is performed more often than kidney transplantation from deceased donors. Germany implemented a transplantation law in December 1997. This law also regulates living donation, with exclusion of crossover transplantations. Cross-over transplantation is a special variation of live donation for couples who cannot donate/receive in their respective couple constellation. Therefore, the donor of the one couple donates his/her kidney to the recipient of the other couple and vice versa. According to German legislation this is illegal. We performed a study in order to evaluate the opinions of the German kidney transplant centers on crossover kidney transplantations. The majority of the German transplantation centers believe that crossover transplantation is acceptable with regard to ethical and medical concerns. To enable this kind of kidney transplantation the transplantation law would have to be changed. Nevertheless, nationwide polls show that live kidney donation represents only a very small portion of all transplantations taking place. Live kidney donation should be granted higher priority as dialysis triggers psychological and physical damage, especially in children. For many patients live kidney donation is the only chance for early transplantation with an excellent long-lasting kidney graft function.

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Year:  2006        PMID: 16328212     DOI: 10.1007/s00120-005-0965-7

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


  30 in total

Review 1.  Living-donor kidney transplantation.

Authors:  G Kirste
Journal:  Langenbecks Arch Surg       Date:  1999-12       Impact factor: 3.445

2.  Paired-kidney-exchange programs.

Authors:  R A Sells
Journal:  N Engl J Med       Date:  1997-11-06       Impact factor: 91.245

3.  Ethics of a paired-kidney-exchange program.

Authors:  L F Ross; D T Rubin; M Siegler; M A Josephson; J R Thistlethwaite; E S Woodle
Journal:  N Engl J Med       Date:  1997-06-12       Impact factor: 91.245

4.  A comparison of populations served by kidney paired donation and list paired donation.

Authors:  Sommer E Gentry; Dorry L Segev; Robert A Montgomery
Journal:  Am J Transplant       Date:  2005-08       Impact factor: 8.086

Review 5.  Immune hemolysis associated with transplantation.

Authors:  Lawrence D Petz
Journal:  Semin Hematol       Date:  2005-07       Impact factor: 3.851

6.  Improved outcomes after ABO-incompatible living-donor kidney transplantation after 4 weeks of treatment with mycophenolate mofetil.

Authors:  Makoto Mannami; Naoki Mitsuhata
Journal:  Transplantation       Date:  2005-06-27       Impact factor: 4.939

7.  Lessons learned from ABO-incompatible living donor kidney transplantation: 20 years later.

Authors:  Jean-Paul Squifflet; Martine De Meyer; Jacques Malaise; Dominique Latinne; Yves Pirson; Guy P J Alexandre
Journal:  Exp Clin Transplant       Date:  2004-06       Impact factor: 0.945

8.  [The Swiss Organ Living Donor Health Registry (SOL-DHR)].

Authors:  G T Thiel; C Nolte; D Tsinalis
Journal:  Ther Umsch       Date:  2005-07

9.  [Basic ethical aspects of living organ donation].

Authors:  E Nagel; J Mayer
Journal:  Chirurg       Date:  2003-06       Impact factor: 0.955

10.  Renal transplant in a patient with major donor-recipient blood group incompatibility: reversal of acute rejection by the use of modified plasmapheresis.

Authors:  M Slapak; R B Naik; H A Lee
Journal:  Transplantation       Date:  1981-01       Impact factor: 4.939

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