J Lange1, N Follak, T Nowotny, H Merk. 1. Klinik und Poliklinik für Orthopädie und Orthopädische Chirurgie, Ernst-Moritz-Arndt-Universität, Greifswald.
Abstract
AIM OF STUDY: This prospective report presents SaluCartilage hydrogel implants, an alternative therapy option in the treatment of chondral defects. METHODS: For the prospective study between October 2002 and July 2003, 18 patients suffering from stage IV chondral defects received 49 hydrogel implants and were subsequently examined by means of clinical, radiological, and magnetic resonance imaging assessment. The knee function was classified using the McDermott score. RESULTS: The average McDermott score was improved to 75 points (p<0.05) after 3 months postoperatively and to 80 points (p<0.05) 6 months postoperatively, but after 12 months it decreased to 69 points. After 3 and 6 months, the MRI showed in all patients that there was fluid around the hydrogel implants without dislocation. After 12 months postoperatively the hydrogel implants had been destroyed in two patients. CONCLUSION: The short-term results showed subjective and objective improvement of the medical conditions probably because of the placeholder function. This alternative should be critically discussed because of the inadequate connection to the bone with risk of dislocation.
AIM OF STUDY: This prospective report presents SaluCartilage hydrogel implants, an alternative therapy option in the treatment of chondral defects. METHODS: For the prospective study between October 2002 and July 2003, 18 patients suffering from stage IV chondral defects received 49 hydrogel implants and were subsequently examined by means of clinical, radiological, and magnetic resonance imaging assessment. The knee function was classified using the McDermott score. RESULTS: The average McDermott score was improved to 75 points (p<0.05) after 3 months postoperatively and to 80 points (p<0.05) 6 months postoperatively, but after 12 months it decreased to 69 points. After 3 and 6 months, the MRI showed in all patients that there was fluid around the hydrogel implants without dislocation. After 12 months postoperatively the hydrogel implants had been destroyed in two patients. CONCLUSION: The short-term results showed subjective and objective improvement of the medical conditions probably because of the placeholder function. This alternative should be critically discussed because of the inadequate connection to the bone with risk of dislocation.
Authors: Sevan R Oungoulian; Kristin E Hehir; Kaicen Zhu; Callen E Willis; Anca G Marinescu; Natasha Merali; Christopher S Ahmad; Clark T Hung; Gerard A Ateshian Journal: J Biomech Date: 2013-12-01 Impact factor: 2.712
Authors: Hang Lin; Anthony Wai-Ming Cheng; Peter G Alexander; Angela M Beck; Rocky S Tuan Journal: Tissue Eng Part A Date: 2014-04-09 Impact factor: 3.845