BACKGROUND: Acromegaly secondary to growth hormone releasing hormone (GHRH) secretion is exceptionally rare. AIM: To report a case of acromegaly diagnosed in 1984 and assumed to be pituitary in origin. Sixteen years later, the cause was found to be a GHRH secreting neuroendocrine pancreatic tumour. METHOD: A case report. CONCLUSION: Although ectopic GHRH production is very rare, endocrinologists should be aware of this possibility in acromegaly patients if a pituitary tumour was not detected using pituitary imaging.
BACKGROUND:Acromegaly secondary to growth hormone releasing hormone (GHRH) secretion is exceptionally rare. AIM: To report a case of acromegaly diagnosed in 1984 and assumed to be pituitary in origin. Sixteen years later, the cause was found to be a GHRH secreting neuroendocrine pancreatic tumour. METHOD: A case report. CONCLUSION: Although ectopic GHRH production is very rare, endocrinologists should be aware of this possibility in acromegalypatients if a pituitary tumour was not detected using pituitary imaging.
Authors: D Chadenas; D Pinsard; D Melliere; J Trouillas; E S Zafrani; L Pradayrol; G Sassolas; Y Li; C Girod; J Aumaitre Journal: Presse Med Date: 1985-12-07 Impact factor: 1.228
Authors: Iga Zendran; Gabriela Gut; Marcin Kałużny; Katarzyna Zawadzka; Marek Bolanowski Journal: Front Endocrinol (Lausanne) Date: 2022-06-09 Impact factor: 6.055
Authors: Nienke R Biermasz; Jan W A Smit; Alberto M Pereira; Marijke Frölich; Johannes A Romijn; Ferdinand Roelfsema Journal: Pituitary Date: 2007 Impact factor: 4.107