Literature DB >> 16321410

Five labdane diterpenoids from the seeds of Aframomum zambesiacum.

Marguerite Kenmogne1, Elise Prost, Dominique Harakat, Marie-José Jacquier, Michel Frédérich, Lucas B Sondengam, Monique Zèches, Pierre Waffo-Téguo.   

Abstract

Five labdane diterpenoids, (3-5), zambesiacolactone A (7) and zambesiacolactone B (8), were isolated from the seeds of Aframomum zambesiacum (Baker) K. Schum., along with five known labdanes and a linear sesquiterpene, nerolidol. Their structures were elucidated by spectroscopic analysis. Their antiplasmodial activity was evaluated in vitro against Plasmodium falciparum. Compound 3 was the most active with an IC(50) value of 4.97 microM.

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Year:  2006        PMID： 16321410     DOI： 10.1016/j.phytochem.2005.10.015

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  9 in total

Review 1.  Plant-derived antimicrobials to fight against multi-drug-resistant human pathogens.

Authors:  Ramesh Subramani; Mathivanan Narayanasamy; Klaus-D Feussner
Journal:  3 Biotech       Date:  2017-06-29       Impact factor: 2.406

2.  The antimalarial potential of medicinal plants used for the treatment of malaria in Cameroonian folk medicine.

Authors:  Vincent P K Titanji; Denis Zofou; Moses N Ngemenya
Journal:  Afr J Tradit Complement Altern Med       Date:  2008-04-10

3.  Anti-plasmodial activity of Dicoma tomentosa (Asteraceae) and identification of urospermal A-15-O-acetate as the main active compound.

Authors:  Olivia Jansen; Monique Tits; Luc Angenot; Jean-Pierre Nicolas; Patrick De Mol; Jean-Baptiste Nikiema; Michel Frédérich
Journal:  Malar J       Date:  2012-08-21       Impact factor: 2.979

4.  Cameroonian medicinal plants: pharmacology and derived natural products.

Authors:  Victor Kuete; Thomas Efferth
Journal:  Front Pharmacol       Date:  2010-10-25       Impact factor: 5.810

5.  Cameroonian medicinal plants: a bioactivity versus ethnobotanical survey and chemotaxonomic classification.

Authors:  Fidele Ntie-Kang; Lydia Likowo Lifongo; Luc Meva'a Mbaze; Nnange Ekwelle; Luc C Owono Owono; Eugene Megnassan; Philip N Judson; Wolfgang Sippl; Simon M N Efange
Journal:  BMC Complement Altern Med       Date:  2013-06-26       Impact factor: 3.659

Review 6.  The potential of anti-malarial compounds derived from African medicinal plants, part I: a pharmacological evaluation of alkaloids and terpenoids.

Authors:  Pascal Amoa Onguéné; Fidele Ntie-Kang; Lydia Likowo Lifongo; Jean Claude Ndom; Wolfgang Sippl; Luc Meva'a Mbaze
Journal:  Malar J       Date:  2013-12-13       Impact factor: 2.979

7.  Carbohydrate Modifications of Neoandrographolide for Improved Reactive Oxygen Species-Mediated Apoptosis through Mitochondrial Pathway in Colon Cancer.

Authors:  Venu Sharma; Arem Qayum; Sanjana Kaul; Ajeet Singh; Kamal K Kapoor; Debaraj Mukherjee; Shashank K Singh; Manoj K Dhar
Journal:  ACS Omega       Date:  2019-11-26

Review 8.  The Antiplasmodial Potential of Medicinal Plants Used in the Cameroonian Pharmacopoeia: An Updated Systematic Review and Meta-Analysis.

Authors:  Arnaud Gabin N Tepa; Panthaleon Ambassa; Lawrence S Ayong; Prosper Cabral Biapa Nya; Constant Anatole Pieme
Journal:  Evid Based Complement Alternat Med       Date:  2022-10-08       Impact factor: 2.650

9.  An Andrographolide from Helichrysum caespitium (DC.) Sond. Ex Harv., (Asteraceae) and Its Antimicrobial, Antiquorum Sensing, and Antibiofilm Potentials.

Authors:  Kokoette Bassey; Patience Mamabolo; Sekelwa Cosa
Journal:  Biology (Basel)       Date:  2021-11-24
  9 in total

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