Literature DB >> 16321035

Convergent stereoselective synthesis of the visual pigment A2E.

Cristina Sicre1, M Magdalena Cid.   

Abstract

[chemical reaction: see text]. A stereoselective total synthesis of the visual pigment A2E has been achieved with use of palladium-catalyzed cross-coupling reactions in all key steps: a regioselective Suzuki or Negishi coupling of 2,4-dibromopyridine, a Sonogashira reaction, and a double Stille cross-coupling to complete the bispolyenyl skeleton.

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Year:  2005        PMID: 16321035     DOI: 10.1021/ol052512u

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

Review 1.  Negishi coupling: an easy progress for C-C bond construction in total synthesis.

Authors:  Majid M Heravi; Elaheh Hashemi; Niousha Nazari
Journal:  Mol Divers       Date:  2014-03-07       Impact factor: 2.943

2.  Morphological and physiological retinal degeneration induced by intravenous delivery of vitamin A dimers in rabbits.

Authors:  Jackie Penn; Doina M Mihai; Ilyas Washington
Journal:  Dis Model Mech       Date:  2014-12-12       Impact factor: 5.758

  2 in total

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