Literature DB >> 16319240

Can artificial parthenogenesis sidestep ethical pitfalls in human therapeutic cloning? An historical perspective.

H Fangerau1.   

Abstract

The aim of regenerative medicine is to reconstruct tissue that has been lost or pathologically altered. Therapeutic cloning seems to offer a method of achieving this aim; however, the ethical debate surrounding human therapeutic cloning is highly controversial. Artificial parthenogenesis-obtaining embryos from unfertilised eggs-seems to offer a way to sidestep these ethical pitfalls. Jacques Loeb (1859-1924), the founding father of artificial parthenogenesis, faced negative public opinion when he published his research in 1899. His research, the public's response to his findings, and his ethical foundations serve as an historical argument both for the communication of science and compromise in biological research.

Entities:  

Keywords:  Biomedical and Behavioral Research; Genetics and Reproduction

Mesh：

Year:  2005        PMID： 16319240      PMCID： PMC1734065          DOI： 10.1136/jme.2004.010199

Source DB:  PubMed          Journal:  J Med Ethics        ISSN： 0306-6800            Impact factor:   2.903


  15 in total

1.  Parthenogenetic stem cells in nonhuman primates.

Authors:  Jose B Cibelli; Kathleen A Grant; Karen B Chapman; Kerrianne Cunniff; Travis Worst; Heather L Green; Stephen J Walker; Philip H Gutin; Lucy Vilner; Viviane Tabar; Tanja Dominko; Jeff Kane; Peter J Wettstein; Robert P Lanza; Lorenz Studer; Kent E Vrana; Michael D West
Journal:  Science       Date:  2002-02-01       Impact factor: 47.728

2.  Stem cell research. Primate parthenotes yield stem cells.

Authors:  Constance Holden
Journal:  Science       Date:  2002-02-01       Impact factor: 47.728

3.  Life in the laboratory: public responses to experimental biology.

Authors:  J Turney
Journal:  Public Underst Sci       Date:  1995-04

Review 4.  Therapeutic and reproductive cloning: a critique.

Authors:  Finn Bowring
Journal:  Soc Sci Med       Date:  2004-01       Impact factor: 4.634

5.  Zones of consensus and zones of conflict: questioning the "common morality" presumption in bioethics.

Authors:  Leigh Turner
Journal:  Kennedy Inst Ethics J       Date:  2003-09

6.  Cell biology. A technical fix for an ethical bind?

Authors:  Constance Holden; Gretchen Vogel
Journal:  Science       Date:  2004-12-24       Impact factor: 47.728

Review 7.  Going to the roots of the stem cell controversy.

Authors:  Soren Holm
Journal:  Bioethics       Date:  2002-11       Impact factor: 1.898

Review 8.  Human embryonic stem cells: research, ethics and policy.

Authors:  Guido de Wert; Christine Mummery
Journal:  Hum Reprod       Date:  2003-04       Impact factor: 6.918

9.  Nonhuman primate parthenogenetic stem cells.

Authors:  Kent E Vrana; Jason D Hipp; Ashley M Goss; Brian A McCool; David R Riddle; Stephen J Walker; Peter J Wettstein; Lorenz P Studer; Viviane Tabar; Kerrianne Cunniff; Karen Chapman; Lucy Vilner; Michael D West; Kathleen A Grant; Jose B Cibelli
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-22       Impact factor: 11.205

10.  Multilineage potential of homozygous stem cells derived from metaphase II oocytes.

Authors:  Helen Lin; JingQi Lei; David Wininger; Minh-Thanh Nguyen; Ruchi Khanna; Chris Hartmann; Wen-Liang Yan; Steve C Huang
Journal:  Stem Cells       Date:  2003       Impact factor: 6.277
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  1 in total

1.  Enhancing effects of serum-rich and cytokine-supplemented culture conditions on developing blastocysts and deriving porcine parthenogenetic embryonic stem cells.

Authors:  Soo-Kyung Jung; Hyun-Jung Kim; Chan-Lan Kim; Joo-Hyeong Lee; Jin-Young You; Eun-Song Lee; Jeong-Mook Lim; Seon Jong Yun; Jae-Young Song; Sang-Ho Cha
Journal:  J Vet Sci       Date:  2014-06-20       Impact factor: 1.672
  1 in total

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