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Literature DB >> 16317474

Inactivation of human angiotensin converting enzyme by copper peptide complexes containing ATCUN motifs.

Abstract

The copper complex [KGHK-Cu]+ demonstrates catalytic inactivation of human angiotensin converting enzyme at sub-saturating concentrations, under oxidative conditions, with an observed rate constant k approximately 2.9 +/- 0.5 x 10(-2) min(-1).

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Year: 2005 PMID： 16317474 DOI： 10.1039/b511081e

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

11 in total

Review 1. Application of metal coordination chemistry to explore and manipulate cell biology.

Authors: Kathryn L Haas; Katherine J Franz
Journal: Chem Rev Date: 2009-10 Impact factor: 60.622

2. Metallopeptide-promoted inactivation of angiotensin-converting enzyme and endothelin-converting enzyme 1: Toward dual-action therapeutics.

Authors: Nikhil H Gokhale; J A Cowan
Journal: J Biol Inorg Chem Date: 2006-07-28 Impact factor: 3.358

3. Metal-binding and redox properties of substituted linear and cyclic ATCUN motifs.

Authors: Kosh P Neupane; Amanda R Aldous; Joshua A Kritzer
Journal: J Inorg Biochem Date: 2014-06-12 Impact factor: 4.155

4. Diamide Inhibitors of the Bacillus subtilis N-Acetylglucosaminidase LytG That Exhibit Antibacterial Activity.

Authors: Saman Nayyab; Mary O'Connor; Jennifer Brewster; James Gravier; Mitchell Jamieson; Ethan Magno; Ryan D Miller; Drew Phelan; Keyana Roohani; Paul Williard; Amit Basu; Christopher W Reid
Journal: ACS Infect Dis Date: 2017-05-08 Impact factor: 5.084

Inactivation of human angiotensin converting enzyme by copper peptide complexes containing ATCUN motifs.

Review 1. Application of metal coordination chemistry to explore and manipulate cell biology.

2. Metallopeptide-promoted inactivation of angiotensin-converting enzyme and endothelin-converting enzyme 1: Toward dual-action therapeutics.

3. Metal-binding and redox properties of substituted linear and cyclic ATCUN motifs.

4. Diamide Inhibitors of the Bacillus subtilis N-Acetylglucosaminidase LytG That Exhibit Antibacterial Activity.

Review 5. Molecular recognition in protein modification with rhodium metallopeptides.

6. Inactivation of sortase A mediated by metal ATCUN complexes.

7. Stimulation and oxidative catalytic inactivation of thermolysin by copper.Cys-Gly-His-Lys.

8. Metallotherapeutics: novel strategies in drug design.

9. Catalytic metallodrugs based on the LaR2C peptide target HCV SLIV IRES RNA.

10. Cellular activity of Rev response element RNA targeting metallopeptides.