Literature DB >> 1631568

Pharmacologic aspects of the development of selective synthetic thrombin inhibitors as anticoagulants.

J Hauptmann1, F Markwardt.   

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Year:  1992        PMID: 1631568     DOI: 10.1055/s-2007-1002426

Source DB:  PubMed          Journal:  Semin Thromb Hemost        ISSN: 0094-6176            Impact factor:   4.180


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  5 in total

1.  Functionality map analysis of the active site cleft of human thrombin.

Authors:  P D Grootenhuis; M Karplus
Journal:  J Comput Aided Mol Des       Date:  1996-02       Impact factor: 3.686

2.  Incorporation of noncoded amino acids into the N-terminal domain 1-47 of hirudin yields a highly potent and selective thrombin inhibitor.

Authors:  V De Filippis; I Russo; A Vindigni; E Di Cera; S Salmaso; A Fontana
Journal:  Protein Sci       Date:  1999-10       Impact factor: 6.725

3.  Crystal structure of two new bifunctional nonsubstrate type thrombin inhibitors complexed with human alpha-thrombin.

Authors:  J Féthière; Y Tsuda; R Coulombe; Y Konishi; M Cygler
Journal:  Protein Sci       Date:  1996-06       Impact factor: 6.725

4.  Benzyloxycarbonyl-D-Phe-Pro-methoxypropylboroglycine: a novel inhibitor of thrombin with high selectivity containing a neutral side chain at the P1 position.

Authors:  G Claeson; M Philipp; E Agner; M F Scully; R Metternich; V V Kakkar; T DeSoyza; L H Niu
Journal:  Biochem J       Date:  1993-03-01       Impact factor: 3.857

5.  Influence of indocyanine green on plasma disappearance and biliary excretion of a synthetic thrombin inhibitor of the 3-amidinophenyl-alanine piperazide-type in rats.

Authors:  J Hauptmann; J Stürzebecher
Journal:  Pharm Res       Date:  1998-05       Impact factor: 4.200

  5 in total

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