Literature DB >> 16315492

Analysis of macamides in samples of Maca (Lepidium meyenii) by HPLC-UV-MS/MS.

Megan M McCollom1, Jacquelyn R Villinski, Kerry L McPhail, Lyle E Craker, Stefan Gafner.   

Abstract

The macamides are a distinct class of secondary metabolites that have so far been found only in Lepidium meyenii Walp. (Maca). Using HPLC-UV-MS/MS, the main macamides have been identified as n-benzylhexadecanamide, n-benzyl-(9Z)-octadecenamide, n-benzyl-(9Z, 12Z)-octadecadienamide, n-benzyl-(9Z, 12Z, 15Z)-octadecatrienamide and n-benzyloctadecanamide. The identities of n-benzyl-(9Z)-octadecenamide and n-benzyl-(9Z, 12Z)-octadecadienamide were confirmed by comparison of chromatographic and spectral properties with synthetic analogues. Total macamides have been quantified by HPLC-UV in plant material from different vendors using n-benzylhexadecanamide as an external standard. The amount of macamides in the dried plant material ranged from 0.0016 to 0.0123%.

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Year:  2005        PMID: 16315492     DOI: 10.1002/pca.871

Source DB:  PubMed          Journal:  Phytochem Anal        ISSN: 0958-0344            Impact factor:   3.373


  14 in total

1.  The macamide N-3-methoxybenzyl-linoleamide is a time-dependent fatty acid amide hydrolase (FAAH) inhibitor.

Authors:  Haifa Almukadi; Hui Wu; Mark Böhlke; Charles J Kelley; Timothy J Maher; Alejandro Pino-Figueroa
Journal:  Mol Neurobiol       Date:  2013-07-14       Impact factor: 5.590

2.  Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands.

Authors:  Gustavo F Gonzales
Journal:  Evid Based Complement Alternat Med       Date:  2011-10-02       Impact factor: 2.629

3.  Effect of Lepidium meyenii Walp. on Semen Parameters and Serum Hormone Levels in Healthy Adult Men: A Double-Blind, Randomized, Placebo-Controlled Pilot Study.

Authors:  Ingrid Melnikovova; Tomas Fait; Michaela Kolarova; Eloy C Fernandez; Luigi Milella
Journal:  Evid Based Complement Alternat Med       Date:  2015-09-01       Impact factor: 2.629

4.  In silico profiling for secondary metabolites from Lepidium meyenii (maca) by the pharmacophore and ligand-shape-based joint approach.

Authors:  Fan Yi; Xiao-Lei Tan; Xin Yan; Hai-Bo Liu
Journal:  Chin Med       Date:  2016-09-26       Impact factor: 5.455

5.  Chemical profiling analysis of Maca using UHPLC-ESI-Orbitrap MS coupled with UHPLC-ESI-QqQ MS and the neuroprotective study on its active ingredients.

Authors:  Yanyan Zhou; Peng Li; Adelheid Brantner; Hongjie Wang; Xinbin Shu; Jian Yang; Nan Si; Lingyu Han; Haiyu Zhao; Baolin Bian
Journal:  Sci Rep       Date:  2017-03-17       Impact factor: 4.379

6.  Optimization of Ultrasound-Assisted Extraction, HPLC and UHPLC-ESI-Q-TOF-MS/MS Analysis of Main Macamides and Macaenes from Maca (Cultivars of Lepidium meyenii Walp).

Authors:  Shu-Xiao Chen; Ke-Ke Li; Duoji Pubu; Si-Ping Jiang; Bin Chen; Li-Rong Chen; Zhen Yang; Chao Ma; Xiao-Jie Gong
Journal:  Molecules       Date:  2017-12-10       Impact factor: 4.411

Review 7.  Progress on the Chemical Constituents Derived from Glucosinolates in Maca (Lepidium meyenii).

Authors:  Yan-Jie Huang; Xing-Rong Peng; Ming-Hua Qiu
Journal:  Nat Prod Bioprospect       Date:  2018-08-27

8.  Differentiation of Lepidium meyenii (Maca) from Different Origins by Electrospray Ionization Mass Spectrometry with Principal Component Analysis.

Authors:  Sihou Yang; Xiaochun Sun; Yumei Gao; Rui Chen
Journal:  ACS Omega       Date:  2019-09-27

9.  Antiviral Activity of Metabolites from Peruvian Plants against SARS-CoV-2: An In Silico Approach.

Authors:  Luis Daniel Goyzueta-Mamani; Haruna Luz Barazorda-Ccahuana; Karel Mena-Ulecia; Miguel Angel Chávez-Fumagalli
Journal:  Molecules       Date:  2021-06-25       Impact factor: 4.411

10.  Peruvian Maca (Lepidium peruvianum): (II) Phytochemical Profiles of Four Prime Maca Phenotypes Grown in Two Geographically-Distant Locations.

Authors:  Henry O Meissner; Alina Mscisz; Ewa Piatkowska; Marek Baraniak; Sebastian Mielcarek; Bogdan Kedzia; Elzbieta Holderna-Kedzia; Pawel Pisulewski
Journal:  Int J Biomed Sci       Date:  2016-03
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