Literature DB >> 16315045

Treatment of large conjunctival nevus by resection and reconstruction using amniotic membrane.

Machiko Tomita1, Hiroshi Goto, Ryuji Muramatsu, Masahiko Usui.   

Abstract

BACKGROUND: Nevus of the bulbar conjunctiva is a benign pigmented lesion of the ocular surface. Unless a biopsy is required for ruling out malignant melanoma, a nevus is usually excised for cosmetic reasons only. However, with large lesions involving two or more quadrants of the bulbar conjunctiva, a total resection can be difficult. In this report, we present a case of a huge nevus treated by surgical excision and amniotic membrane transplantation for reconstruction of the bulbar conjunctiva.
METHODS: A 54-year-old Japanese man was referred to our clinic with suspected malignant tumor of the bulbar conjunctiva in his right eye. A large and diffuse pigmented tumor with numerous small cysts was present mainly on the upper bulbar conjunctiva. Resection of the conjunctival tumor and amniotic membrane transplantation for reconstruction of the bulbar conjunctiva were performed.
RESULTS: The histopathological diagnosis was conjunctival nevus. Epithelialization of the bulbar conjunctiva over the amniotic membrane sheet was completed 4 weeks after resection. At 44-month follow-up, there was no recurrence or any postoperative complication.
CONCLUSION: Surgical resection combined with reconstruction by amniotic membrane transplantation is effective for the treatment of large conjunctival nevus.

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Year:  2005        PMID: 16315045     DOI: 10.1007/s00417-005-0160-y

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  9 in total

Review 1.  Amniotic membrane transplantation for ocular surface reconstruction.

Authors:  S C Tseng
Journal:  Biosci Rep       Date:  2001-08       Impact factor: 3.840

2.  Efficacy of (123)N-isopropyl-p-[(123)I]-iodoamphetamine single photon emission computed tomography for the diagnosis of uveal malignant melanoma.

Authors:  H Goto; M Usui; I Ishii
Journal:  Am J Ophthalmol       Date:  2001-12       Impact factor: 5.258

3.  Amniotic membrane transplantation in the management of conjunctival malignant melanoma and primary acquired melanosis with atypia.

Authors:  D Paridaens; H Beekhuis; W van Den Bosch; L Remeyer; G Melles
Journal:  Br J Ophthalmol       Date:  2001-06       Impact factor: 4.638

4.  Amniotic membrane transplantation for conjunctival surface reconstruction.

Authors:  S C Tseng; P Prabhasawat; S H Lee
Journal:  Am J Ophthalmol       Date:  1997-12       Impact factor: 5.258

5.  Management of conjunctival and corneal melanoma with surgical excision, amniotic membrane allograft, and topical chemotherapy.

Authors:  C L Shields; J A Shields; T Armstrong
Journal:  Am J Ophthalmol       Date:  2001-10       Impact factor: 5.258

6.  5-S-cysteinyldopa as diagnostic tumor marker for uveal malignant melanoma.

Authors:  H Goto; M Usui; K Wakamatsu; S Ito
Journal:  Jpn J Ophthalmol       Date:  2001 Sep-Oct       Impact factor: 2.447

7.  Reconstruction of the ocular surface by transplantation of a serum-free derived cultivated conjunctival epithelial equivalent.

Authors:  Donald T H Tan; Leonard P K Ang; Roger W Beuerman
Journal:  Transplantation       Date:  2004-06-15       Impact factor: 4.939

Review 8.  Clinicopathologic characteristics of premalignant and malignant melanocytic lesions of the conjunctiva.

Authors:  F A Jakobiec; R Folberg; T Iwamoto
Journal:  Ophthalmology       Date:  1989-02       Impact factor: 12.079

Review 9.  Benign conjunctival melanocytic lesions. Clinicopathologic features.

Authors:  R Folberg; F A Jakobiec; V B Bernardino; T Iwamoto
Journal:  Ophthalmology       Date:  1989-04       Impact factor: 12.079

  9 in total
  2 in total

1.  Sutureless amniotic membrane transplantation following excision of ocular surface neoplasia.

Authors:  Altan Ozcan; Ebru Esen; Emine Ciloglu
Journal:  Int J Ophthalmol       Date:  2015-06-18       Impact factor: 1.779

2.  Case of a Giant Conjunctival Melanocytic Nevus.

Authors:  Hidetsugu Mori; Kanji Takahashi
Journal:  Ocul Oncol Pathol       Date:  2020-12-18
  2 in total

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