| Literature DB >> 16314082 |
Kalpana Joshi1, Sagar Lad, Mrudula Kale, Bhushan Patwardhan, Sahebrao P Mahadik, Bindu Patni, Arti Chaudhary, Sheila Bhave, Anand Pandit.
Abstract
Considerable clinical and experimental evidence now supports the idea that deficiencies or imbalances in certain highly unsaturated fatty acids may contribute to a range of common developmental disorders including Attention Deficit Hyperactivity Disorder (ADHD). Few intervention studies with LCPUFA supplementation have reported inconsistent and marginal results. This pilot study evaluates the effect of alpha linolenic acid (ALA)-rich nutritional supplementation in the form of flax oil and antioxidant emulsion on blood fatty acids composition and behavior in children with ADHD. Post-supplementation levels of RBC membrane fatty acids were significantly higher than pretreatment levels as well as the levels in control. There was significant improvement in the symptoms of ADHD reflected by reduction in total hyperactivity scores of ADHD children derived from ADHD rating scale.Entities:
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Year: 2005 PMID： 16314082 DOI： 10.1016/j.plefa.2005.10.001
Source DB: PubMed Journal: Prostaglandins Leukot Essent Fatty Acids ISSN： 0952-3278 Impact factor: 4.006