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Literature DB >> 16312051

Oligo- and poly-nucleotides: 50 years of chemical synthesis.

Abstract

It is fifty years since the first chemical synthesis of a dinucleoside phosphate and a dinucleotide with natural 3'-->5'-internucleotide linkages was reported. The main developments in the methodology of oligo- and poly-nucleotide synthesis that have taken place since are described.

Entities: Chemical

Mesh：

Substances：

Year: 2005 PMID： 16312051 DOI： 10.1039/b510458k

Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876

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Cited

24 in total

1. New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes.

Authors: Afaf H El-Sagheer; Tom Brown
Journal: Proc Natl Acad Sci U S A Date: 2010-08-16 Impact factor: 11.205

2. Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling.

Authors: William M Rockey; Frank J Hernandez; Sheng-You Huang; Song Cao; Craig A Howell; Gregory S Thomas; Xiu Ying Liu; Natalia Lapteva; David M Spencer; James O McNamara; Xiaoqin Zou; Shi-Jie Chen; Paloma H Giangrande
Journal: Nucleic Acid Ther Date: 2011-10 Impact factor: 5.486

3. DETECTING LOW-LEVEL SYNTHESIS IMPURITIES IN MODIFIED PHOSPHOROTHIOATE OLIGONUCLEOTIDES USING LIQUID CHROMATOGRAPHY - HIGH RESOLUTION MASS SPECTROMETRY.

Authors: Irena Nikcevic; Tadeusz K Wyrzykiewicz; Patrick A Limbach
Journal: Int J Mass Spectrom Date: 2011-07-01 Impact factor: 1.986

4. Nucleotide bias observed with a short SELEX RNA aptamer library.

Authors: William H Thiel; Thomas Bair; Kristina Wyatt Thiel; Justin P Dassie; William M Rockey; Craig A Howell; Xiuying Y Liu; Adam J Dupuy; Lingyan Huang; Richard Owczarzy; Mark A Behlke; James O McNamara; Paloma H Giangrande
Journal: Nucleic Acid Ther Date: 2011-06-28 Impact factor: 5.486

5. Biocompatible artificial DNA linker that is read through by DNA polymerases and is functional in Escherichia coli.

Authors: Afaf H El-Sagheer; A Pia Sanzone; Rachel Gao; Ali Tavassoli; Tom Brown
Journal: Proc Natl Acad Sci U S A Date: 2011-06-27 Impact factor: 11.205

6. Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications.

Authors: Bryan R Meade; Khirud Gogoi; Alexander S Hamil; Caroline Palm-Apergi; Arjen van den Berg; Jonathan C Hagopian; Aaron D Springer; Akiko Eguchi; Apollo D Kacsinta; Connor F Dowdy; Asaf Presente; Peter Lönn; Manuel Kaulich; Naohisa Yoshioka; Edwige Gros; Xian-Shu Cui; Steven F Dowdy
Journal: Nat Biotechnol Date: 2014-11-17 Impact factor: 54.908

Oligo- and poly-nucleotides: 50 years of chemical synthesis.

1. New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes.

2. Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling.

3. DETECTING LOW-LEVEL SYNTHESIS IMPURITIES IN MODIFIED PHOSPHOROTHIOATE OLIGONUCLEOTIDES USING LIQUID CHROMATOGRAPHY - HIGH RESOLUTION MASS SPECTROMETRY.

4. Nucleotide bias observed with a short SELEX RNA aptamer library.

5. Biocompatible artificial DNA linker that is read through by DNA polymerases and is functional in Escherichia coli.

6. Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications.

7. Biotechnological mass production of DNA origami.

8. dM-Dim for Carboxylic Acid Protection.

Review 9. Functional protein nanostructures: a chemical toolbox.

10. Synthesis of DNA fragments in yeast by one-step assembly of overlapping oligonucleotides.