BACKGROUND: We have used a schedule for soft x-ray therapy of epithelial malignancies that takes into account the clinically diagnosed tumor involution under treatment. OBJECTIVE: We sought to evaluate the effectiveness of this schedule in terms of cure rate and late ulcerations. METHODS: Patients with 1267 consecutively irradiated (1988-1992) basal cell and squamous cell carcinomas were followed up (average 77 months). RESULTS: The recurrence rate (5.1%) was related to tumor size and thickness and to the time-dose-fractionation factor. The frequency of ulcerations (6.3%) depended on field size, hardness of the x-rays, and in smaller fields (diameter up to 4 cm) on total dose, and time-dose-fractionation factor. Of all ulcerations, 82.5 % could be conservatively cured. LIMITATIONS: We have no evidence that our radiation schedule is superior to those published by other authors. CONCLUSION: These results verify the usefulness of soft x-ray therapy for cutaneous epithelial malignancies.
BACKGROUND: We have used a schedule for soft x-ray therapy of epithelial malignancies that takes into account the clinically diagnosed tumor involution under treatment. OBJECTIVE: We sought to evaluate the effectiveness of this schedule in terms of cure rate and late ulcerations. METHODS:Patients with 1267 consecutively irradiated (1988-1992) basal cell and squamous cell carcinomas were followed up (average 77 months). RESULTS: The recurrence rate (5.1%) was related to tumor size and thickness and to the time-dose-fractionation factor. The frequency of ulcerations (6.3%) depended on field size, hardness of the x-rays, and in smaller fields (diameter up to 4 cm) on total dose, and time-dose-fractionation factor. Of all ulcerations, 82.5 % could be conservatively cured. LIMITATIONS: We have no evidence that our radiation schedule is superior to those published by other authors. CONCLUSION: These results verify the usefulness of soft x-ray therapy for cutaneous epithelial malignancies.
Authors: Mark S Nestor; Brian Berman; David Goldberg; Armand B Cognetta; Michael Gold; William Roth; Clay J Cockerell; Brad Glick Journal: J Clin Aesthet Dermatol Date: 2019-02-01
Authors: Nicholas G Zaorsky; Charles T Lee; Eddie Zhang; Scott W Keith; Thomas J Galloway Journal: Radiother Oncol Date: 2017-08-23 Impact factor: 6.280
Authors: Anna O Likhacheva; Phillip M Devlin; Shervin M Shirvani; Christopher A Barker; Phillip Beron; Ajay Bhatnagar; Stephen W Doggett; Lawrence Hochman; Charles Hsu; Michael Kasper; Martin Keisch; Subhakar Mutyala; Bradley Prestidge; Silvia Rodriguez Villalba; Vershalee Shukla; Srinath Sundararaman; Mitchell Kamrava Journal: Brachytherapy Date: 2016-11-28 Impact factor: 2.362
Authors: Sofian Benkhaled; Dirk Van Gestel; Carolina Gomes da Silveira Cauduro; Samuel Palumbo; Veronique Del Marmol; Antoine Desmet Journal: Front Med (Lausanne) Date: 2022-06-27