Literature DB >> 16309907

Androstenediol analogs as ER-beta-selective SERMs.

Timothy A Blizzard1, Candido Gude, Jerry D Morgan, Wanda Chan, Elizabeth T Birzin, Marina Mojena, Consuelo Tudela, Fang Chen, Kristin Knecht, Qin Su, Bryan Kraker, Ralph T Mosley, Mark A Holmes, Nandini Sharma, Paula M D Fitzgerald, Susan P Rohrer, Milton L Hammond.   

Abstract

A series of 19-substituted androstenediol derivatives was prepared. Some of the novel analogs were surprisingly potent and selective ligands for ER-beta.

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Year:  2005        PMID: 16309907     DOI: 10.1016/j.bmcl.2005.11.014

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  7 in total

1.  Cascade resulting in the reductive ethynylation of aldehydes: dissection of its components.

Authors:  Dongjoo Lee; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2010-03-31       Impact factor: 15.419

Review 2.  Structural and Functional Diversity of Estrogen Receptor Ligands.

Authors:  Amjad Farooq
Journal:  Curr Top Med Chem       Date:  2015       Impact factor: 3.295

3.  Estrogen receptor beta expression in the embryonic brain regulates development of calretinin-immunoreactive GABAergic interneurons.

Authors:  Xiaotang Fan; Margaret Warner; Jan-Ake Gustafsson
Journal:  Proc Natl Acad Sci U S A       Date:  2006-12-11       Impact factor: 11.205

Review 4.  Pathways to tamoxifen resistance.

Authors:  Rebecca B Riggins; Randy S Schrecengost; Michael S Guerrero; Amy H Bouton
Journal:  Cancer Lett       Date:  2007-05-01       Impact factor: 8.679

5.  From Metallacycle-Mediated Annulative Cross-Coupling to Steroidal Tetracycles through Intramolecular C9-C10 Bond Formation.

Authors:  Adam B Millham; Chinmay P Bhatt; Glenn C Micalizio
Journal:  Org Lett       Date:  2020-08-12       Impact factor: 6.005

6.  A screening cascade to identify ERβ ligands.

Authors:  Carly S Filgueira; Cindy Benod; Xiaohua Lou; Prem S Gunamalai; Rosa A Villagomez; Anders Strom; Jan-Åke Gustafsson; Anders L Berkenstam; Paul Webb
Journal:  Nucl Recept Signal       Date:  2014-11-04

7.  A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ.

Authors:  Wan Shin Kim; Zachary A Shalit; Sidney M Nguyen; Emmalie Schoepke; Alan Eastman; Thomas P Burris; Arti B Gaur; Glenn C Micalizio
Journal:  Nat Commun       Date:  2019-06-04       Impact factor: 14.919

  7 in total

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