Literature DB >> 16307545

Successful treatment of a patient with chronic lymphocytic leukaemia (CLL) presenting with bony metastases with aggressive antibody and chemotherapy.

H Narayan1, D Bandyopadhyay, K Schmidt, N Chachlani, M Hughes, S Paneesha, P Rose, A Borg.   

Abstract

Osteolytic lesions are rare in chronic lymphocytic leukaemia (CLL) and thought to result from Richter's transformation or metastatic disease from nonlymphoid malignancies. We report a patient who presented with a large femoral metastatic lesion and hypercalcaemia caused by CLL itself. Complete remission of CLL with resolution of the osteolytic lesion was achieved with rituximab and cyclophosphamide, adriamycin, oncovin and prednisolone [CHOP (R-CHOP)] combination chemotherapy.

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Year:  2005        PMID： 16307545     DOI： 10.1111/j.1365-2257.2005.00733.x

Source DB:  PubMed          Journal:  Clin Lab Haematol        ISSN： 0141-9854


  4 in total

1.  The Risk of Misdiagnosing the Primary Site Responsible for Bone Metastases in Patients With Chronic Lymphocytic Leukemia and a Second Primary Carcinoma.

Authors:  Georges Hatoum; Cyrus Meshkin; Sufana Alkhunaizi; Richard Levene; Julie Formoso-Onofrio
Journal:  World J Oncol       Date:  2015-04-12

2.  Solitary Lytic Bone Metastasis: A Rare Presentation of Small Lymphocytic Leukemia.

Authors:  Heather Katz; Steven Sagun; Doreen Griswold; Mohamed Alsharedi
Journal:  Case Rep Hematol       Date:  2018-10-30

3.  A rare case of appendicular skeleton localization in a patient with chronic lymphocytic leukemia successfully treated with salvage radiation therapy.

Authors:  Carmelo Tuscano; Iolanda Donatella Vincelli; Demetrio Arico'; Anna Maria Marchione; Paolo Versace; Caterina Stelitano; Natale Porta; Vincenzo Petrozza; Claudio Di Cristofano; Giuseppe Sceni; Francesca Ronco; Elvio Grazioso Russi; Said Al Sayyad
Journal:  Adv Radiat Oncol       Date:  2017-01-25

4.  A case of bone lesion in a patient with relapsed chronic lymphocytic leukemia and review of the literature.

Authors:  Francesca Bacchiarri; Alessandro Gozzetti; Nicola Mondanelli; Stefano Lazzi; Monica Bocchia
Journal:  Clin Case Rep       Date:  2022-04-04
  4 in total

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