Literature DB >> 16307537

Platelet size has diagnostic predictive value in patients with thrombocytopenia.

K M Bowles1, L J Cooke, E M Richards, T P Baglin.   

Abstract

We studied 473 unselected patients with thrombocytopenia. The mean platelet volume (MPV) was 8.1 fl in patients with marrow disease and 9.8 fl in patients without marrow disease (P < 0.001). A total of 5% of patients with an MPV >or=10.5 fl have marrow disease (odds ratio 0.05, 95% CI 0.02-0.13). Conversely over three quarters of patients with an MPV of <8.0 fl have marrow disease (odds ratio 8.1, 95% CI 5.0-13.0). Therefore the MPV can strongly guide the clinician as to the likely presence or absence of bone marrow disease in thrombocytopenic patients.

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Year:  2005        PMID： 16307537     DOI： 10.1111/j.1365-2257.2005.00726.x

Source DB:  PubMed          Journal:  Clin Lab Haematol        ISSN： 0141-9854


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