Literature DB >> 16307377

Chemical genetics: Drug screens in Zebrafish.

Jeroen den Hertog1.   

Abstract

High throughput chemical genetic screens for compounds with specific biological activity in a whole organism are feasible using zebrafish embryos. At least two medium to large scale drug screens have been carried out to date, leading to the identification of compounds that disturb zebrafish development. Chemical genetics using zebrafish embryos may become an important step in the discovery of drugs and their targets.

Entities:  

Mesh：

Year:  2005        PMID： 16307377     DOI： 10.1007/s10540-005-2891-8

Source DB:  PubMed          Journal:  Biosci Rep        ISSN： 0144-8463            Impact factor:   3.840


  33 in total

Review 1.  A high-content screening assay in transgenic zebrafish identifies two novel activators of fgf signaling.

Authors:  Manush Saydmohammed; Laura L Vollmer; Ezenwa Obi Onuoha; Andreas Vogt; Michael Tsang
Journal:  Birth Defects Res C Embryo Today       Date:  2011-09

2.  Random walk of single gold nanoparticles in zebrafish embryos leading to stochastic toxic effects on embryonic developments.

Authors:  Lauren M Browning; Kerry J Lee; Tao Huang; Prakash D Nallathamby; Jill E Lowman; Xiao-Hong Nancy Xu
Journal:  Nanoscale       Date:  2009-08-28       Impact factor: 7.790

3.  Silver nanoparticles incite size- and dose-dependent developmental phenotypes and nanotoxicity in zebrafish embryos.

Authors:  Lauren M Browning; Kerry J Lee; Prakash D Nallathamby; Xiao-Hong Nancy Xu
Journal:  Chem Res Toxicol       Date:  2013-09-11       Impact factor: 3.739

4.  In vivo imaging of transport and biocompatibility of single silver nanoparticles in early development of zebrafish embryos.

Authors:  Kerry J Lee; Prakash D Nallathamby; Lauren M Browning; Christopher J Osgood; Xiao-Hong Nancy Xu
Journal:  ACS Nano       Date:  2007-09       Impact factor: 15.881

Review 5.  Skeletal muscle tissue engineering: methods to form skeletal myotubes and their applications.

Authors:  Serge Ostrovidov; Vahid Hosseini; Samad Ahadian; Toshinori Fujie; Selvakumar Prakash Parthiban; Murugan Ramalingam; Hojae Bae; Hirokazu Kaji; Ali Khademhosseini
Journal:  Tissue Eng Part B Rev       Date:  2014-02-24       Impact factor: 6.389

6.  Study of charge-dependent transport and toxicity of peptide-functionalized silver nanoparticles using zebrafish embryos and single nanoparticle plasmonic spectroscopy.

Authors:  Kerry J Lee; Lauren M Browning; Prakash D Nallathamby; Xiao-Hong Nancy Xu
Journal:  Chem Res Toxicol       Date:  2013-05-17       Impact factor: 3.739

7.  Surface functionalities of gold nanoparticles impact embryonic gene expression responses.

Authors:  Lisa Truong; Susan C Tilton; Tatiana Zaikova; Erik Richman; Katrina M Waters; James E Hutchison; Robert L Tanguay
Journal:  Nanotoxicology       Date:  2012-01-20       Impact factor: 5.913

8.  Effect of cerium oxide nanoparticles on intestinal serotonin in zebrafish.

Authors:  Rıfat Emrah Ozel; Akhtar Hayat; Kenneth N Wallace; Silvana Andreescu
Journal:  RSC Adv       Date:  2013-09-21       Impact factor: 3.361

9.  Preparation of water soluble carbon nanotubes and assessment of their biological activity in embryonic zebrafish.

Authors:  Adeniyi A Adenuga; Lisa Truong; Robert L Tanguay; Vincent T Remcho
Journal:  Int J Biomed Nanosci Nanotechnol       Date:  2013-01-01

10.  Design of stable and uniform single nanoparticle photonics for in vivo dynamics imaging of nanoenvironments of zebrafish embryonic fluids.

Authors:  Prakash D Nallathamby; Kerry J Lee; Xiao-Hong Nancy Xu
Journal:  ACS Nano       Date:  2008-07       Impact factor: 15.881
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.