Literature DB >> 16307148

Cyclic sulfamidates as lactam precursors. An efficient asymmetric synthesis of (-)-aphanorphine.

John F Bower1, Peter Szeto, Timothy Gallagher.   

Abstract

A short and efficient enantioselective synthesis of (-)-aphanorphine is described based on the use of a cyclic sulfamidate to provide a suitably functionalised lactam that allows for construction of the tricyclic 3-benzazepine scaffold.

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Year:  2005        PMID: 16307148     DOI: 10.1039/b510761j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  3 in total

1.  Enantioconvergent synthesis of (+)-aphanorphine via asymmetric Pd-catalyzed alkene carboamination.

Authors:  Duy N Mai; Brandon R Rosen; John P Wolfe
Journal:  Org Lett       Date:  2011-05-10       Impact factor: 6.005

Review 2.  Applications of Friedel-Crafts reactions in total synthesis of natural products.

Authors:  Majid M Heravi; Vahideh Zadsirjan; Pegah Saedi; Tayebeh Momeni
Journal:  RSC Adv       Date:  2018-12-03       Impact factor: 4.036

3.  A two step synthesis of a key unit B precursor of cryptophycins by asymmetric hydrogenation.

Authors:  Benedikt Sammet; Mathilde Brax; Norbert Sewald
Journal:  Beilstein J Org Chem       Date:  2011-02-22       Impact factor: 2.883

  3 in total

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