Literature DB >> 16307143

Expanding functionality of RNA: synthesis and properties of RNA containing imidazole modified tandem G-U wobble base pairs.

Eriks Rozners1, Romualdas Smicius, Chika Uchiyama.   

Abstract

Imidazole modification at C-5 of uridine that is part of tandem G-U wobble base pairs causes slight reduction of thermal stability (DeltaDeltaG(0)(310) < 0.4 kcal mol(-1)) and relatively small change in hydration of short RNA helices.

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Year:  2005        PMID： 16307143     DOI： 10.1039/b510846b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Determination of nucleic acid hydration using osmotic stress.

Authors:  Eriks Rozners
Journal:  Curr Protoc Nucleic Acid Chem       Date:  2010-12

2.  Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA.

Authors:  Pradeep S Pallan; Emily M Greene; Paul Andrei Jicman; Rajendra K Pandey; Muthiah Manoharan; Eriks Rozners; Martin Egli
Journal:  Nucleic Acids Res       Date:  2010-12-22       Impact factor: 16.971

3.  Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.

Authors:  Feng Li; Pradeep S Pallan; Martin A Maier; Kallanthottathil G Rajeev; Steven L Mathieu; Christoph Kreutz; Yupeng Fan; Jayodita Sanghvi; Ronald Micura; Eriks Rozners; Muthiah Manoharan; Martin Egli
Journal:  Nucleic Acids Res       Date:  2007-09-18       Impact factor: 16.971

4.  New Metal-Free Route towards Imidazole-Substituted Uridine.

Authors:  Henri-Philippe Mattelaer; Anne-Sophie Van Hool; Flip de Jong; Mark Van der Auweraer; Luc Van Meervelt; Wim Dehaen; Piet Herdewijn
Journal:  European J Org Chem       Date:  2020-06-16
  4 in total

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