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Literature DB >> 16307130

Tumor angiogenic vasculature targeting with PAMAM dendrimer-RGD conjugates.

Rameshwer Shukla¹, Thommey P Thomas, Jennifer Peters, Alina Kotlyar, Andrzej Myc, James R Baker.

Abstract

PAMAM dendrimer-RGD-4C peptide conjugate was synthesized and in vitro targeting efficacy to integrin receptor expressing cells was studied by flow cytometry and confocal microscopy.

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Year: 2005 PMID： 16307130 DOI： 10.1039/b507350b

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

51 in total

1. Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting.

Authors: Ming-Hsin Li; Seok Ki Choi; Thommey P Thomas; Ankur Desai; Kyung-Hoon Lee; Alina Kotlyar; Mark M Banaszak Holl; James R Baker
Journal: Eur J Med Chem Date: 2011-11-23 Impact factor: 6.514

2. Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform.

Authors: Douglas G Mullen; Daniel Q McNerny; Ankur Desai; Xue-Min Cheng; Stassi C Dimaggio; Alina Kotlyar; Yueyang Zhong; Suyang Qin; Christopher V Kelly; Thommey P Thomas; Istvan Majoros; Bradford G Orr; James R Baker; Mark M Banaszak Holl
Journal: Bioconjug Chem Date: 2011-03-22 Impact factor: 4.774

Tumor angiogenic vasculature targeting with PAMAM dendrimer-RGD conjugates.

1. Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting.

2. Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform.

3. Peptide ligands that use a novel binding site to target both TGF-β receptors.

Review 4. Nanomedicines based on recombinant fusion proteins for targeting therapeutic siRNA oligonucleotides.

5. Binding and transport of PAMAM-RGD in a tumor spheroid model: the effect of RGD targeting ligand density.

6. Polyfluorophores on a DNA backbone: a multicolor set of labels excited at one wavelength.

7. Peptide- and saccharide-conjugated dendrimers for targeted drug delivery: a concise review.

8. Targeting the efficacy of a dendrimer-based nanotherapeutic in heterogeneous xenograft tumors in vivo.

9. PAMAM-RGD conjugates enhance siRNA delivery through a multicellular spheroid model of malignant glioma.

10. DNA nanotubes as combinatorial vehicles for cellular delivery.